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Release of catecholamines from pyrenylmethyl urethane conjugates by light
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1  Centro de Química, Universidade do Minho, Campus de Gualtar, 4710-057 Braga, Portugal

Abstract: A fluorescent pyrenylmethyl moiety was coupled to the N-terminus of a series of catecholamines. The behaviour of the corresponding fluorescent conjugates towards photocleavage was evaluated by irradiation in MeOH/HEPES buffer (80:20) solution, in a photochemical reactor at different wavelengths (254, 300, 350 and 419 nm), followed by HPLC/UV monitoring.
Keywords: Pyrene; Catecholamines; Photocleavable protecting groups