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Release of catecholamines from pyrenylmethyl urethane conjugates by light
Published: 31 October 2009 by MDPI in The 13th International Electronic Conference on Synthetic Organic Chemistry session General Organic Synthesis
Abstract: A fluorescent pyrenylmethyl moiety was coupled to the N-terminus of a series of catecholamines. The behaviour of the corresponding fluorescent conjugates towards photocleavage was evaluated by irradiation in MeOH/HEPES buffer (80:20) solution, in a photochemical reactor at different wavelengths (254, 300, 350 and 419 nm), followed by HPLC/UV monitoring.
Keywords: Pyrene; Catecholamines; Photocleavable protecting groups