The "Portioning-Mixing" (Split-Mix) Synthesis

Árpád Furka

doi:10.3390/ecsoc-2-01687

We are working on a new version of the website! To complete the upgrade, Sciforum will be unavailable on Saturday 18 July from 09:00 to 15:00 CEST. Thank you for your understanding.

Previous Article in event

Polyalkoxy Nitrones as Chiral Building Blocks in Asymmetric Synthesis

Next Article in event

Highly efficient and versatile Synthesis of Libraries of constrained b-strand Mimetics

The "Portioning-Mixing" (Split-Mix) Synthesis

Árpád Furka

¹ Advanced ChemTech Inc. 5609 Fern Valley Road, Louisville, KY 40228, USA

Published: 01 November 1998 by MDPI in The 2nd International Electronic Conference on Synthetic Organic Chemistry session Combinatorial Synthesis, Parallel Synthesis and Automation

https://doi.org/10.3390/ecsoc-2-01687

Abstract: The portioning-mixing (PM) procedure is one of the earliest combinatorial synthetic methods. It was introduced 10 years ago, in 1988 [1]-[3]. This method exemplified the first time that it is possible to prepare with high confidence a previously unimaginable large number of compounds. It taught a large number of chemists to think combinatorially. The tenth anniversary of the method offers an occasion to summarize its main advantages, the areas of application and new developments.

Keywords: n/a

View paper

80 Reads

Árpád Furka