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Predicting the Probable Receptor Targets for a Potential Drugs Based on the Assessment of Their Similarity With Endogenous Ligands
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1  Institute of Biomedical Chemistry RAMS, Pogodinskaya Street, 10, Moscow, 119832, Russia

Abstract: Todays pharmacology supposes that pharmaceutical agents interact with various physiological receptors which are the targets for neurotransmitters, hormones and other endogenous bioregulators [1]. The same physiological effects can be induced by activation/inhibition of different receptors. Contrary, interaction with several receptors can decrease the effects, induced by each receptor separately. Therefore, the prediction of probable receptor targets for substance is important for design of agent with desirable pharmacological effect.
Keywords: n/a