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2-Methylbenzothiazole synthesis from 2-Mercaptoaniline and Acetic Acid
* 1 , 2 , 2
1  Scientific-Research Phototechnical Institute on Slavich Company (NIFTI-Slavich) Mendeleev sq. 2, Pereslavl-Zalesskii, Yaroslavl region, 152140, Russian Federation
2  Technologist Co., Ltd., Mendeleev sq.2, Pereslavl-Zalesskii, Yaroslavl region,152140, Russian Federation

Abstract: 2-Methylbenzothiazole is widely used as the half-product for the thiocyanine dyes photosensitisers synthesis. It usually is synthesized by action of an acetic anhydride in excess on 2-mercaptoaniline. High-temperature reaction of 2-mercaptoaniline derivatives with the organic acids at temperatures above 200oC was extensively studied, but the reaction with acetic acid was not described [1-5]. The method of benzothiazole and its lower 2-alkylsubstituted derivatives synthesis from zinc 2-aminomercaptide and lower aliphatic acids was earlier described, but even in this paper in the examples of 2-methylbenzothiazole synthesis acetic anhydride alone or its mixture with benzene was used [6]. We have elaborated a new efficient method of 2-methylbenzothiazole synthesis from 2-mercaptoaniline and acetic acid shown at the scheme 1
Keywords: thiocyanines synthesis half-product, 2-methylbenzothiazole, 2-methylbenzothiazole synthesis, 2-mercaptoaniline.