During biological evolution, numerous organisms have developed hair-like attachment structures to achieve stable adhesion on diverse surfaces. This has inspired researchers to explore biomimetic adhesive microstructures, wherein mushroom-shaped structures have received extensive attention, while spatula-shaped ones better suited for adhesion on rough surfaces have received comparatively less. Here, we present two bio-inspired adhesive prototypes, both featuring an inclined seta and spatulate tip. One prototype incorporates a variable cross-section cylinder with a leaflike thin plate, while the other comprises a uniform cross-section square column and a wedge thick plate, exhibiting geometric transition at the seta-tip joint. Finite element analysis is utilized to investigate the adhesive contact behaviours of these prototypes under vertical displacement on surfaces with varying roughness, specifically asperity radii of 30 nm, 1 μm and infinity (flat surface). The results reveal that compared to the surface with a 30 nm radius asperity, the spatula could adapt relatively well to the single asperity with a 1 μm radius due to such asymmetric structures, which also lead to a leverage phenomenon that will compete with adhesive forces and encourage the contact surfaces to separate. Although the thicker spatula tip exhibits poor flexibility, resulting in reduced effective contact area and adhesion, it may allow the regulation of attachment under unidirectional loading. This study contributes novel insights into the contact behaviour of spatula-shaped adhesive structures and provides valuable inspiration for the future development of artificial adhesives.