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SYNTHESIS OF BENZENE-1,2,3-TRIYL TRIS(2-(2-HYDROXYACETYL)ACETATE) AND BENZENE-1,2,4-TRIYL TRIS(2-(2-HYDROXYACETYL)ACETATE)
1  Shakhrisabz Branch of Tashkent Institute of Chemical Technology, 20, Shahrisabz str., Shakhrisabz 181306, Uzbekistan;
Academic Editor: Blaž Likozar

Abstract:

The potential for triatomic phenols to significantly advance organic chemistry and other domains makes their chloroacetylation and synthesis based on chloroacetyl products relevant. The creation of novel materials, medicines, and specialized compounds is made possible by this variety. Chloroacetylation yields functional groups called chloroacetyls, which can be used as adaptable building blocks for further alterations. It offers a methodical approach to the synthesis of complicated compounds, enhancing the arsenal of tools available to synthetic chemists. Researching novel synthetic routes frequently yields surprising findings and novel ideas. Through the discovery of novel reaction processes, reactivity patterns, and applications, the study of chloroacetylation in the context of triatomic phenols can foster scientific creativity.

In analytical chemistry, phenols and oxycarboxylic acids are employed to identify and measure metal ions. We therefore made the decision to link these two categories of chemicals. With synthesis, a vast array of substances with distinct structures and qualities may be produced.

The syntheses based on the topic "Chloroacetylation of trihydroxybenzenes and Syntheses Based on Chloroacetyl Compounds" are described in this article. O-chloroacetylation reactions were carried out in the presence of trihydroxybenzenes: benzene-1,2,3-triol, benzene-1,2,4-triol and chloroacetyl chloride. Benzene-1,2,3-triyl tris(2-chloroacetate) and benzene-1,2,4-triyl tris(2-chloroacetate) were produced as a consequence of the nucleophilic exchange of chlorine atoms. The sodium salt of tartaric acid (sodium (2S,2R)-3-carboxy-2,3-dihydroxypropanoate) was present during the procedure. The solvent that was employed was dimethylformamide. Using contemporary physicochemical techniques, the structure of the substance that was produced as a result of the reaction was examined. Both the reaction's mechanism and methods were examined.

Keywords: trihydroxybenzene, benzene-1,2,3-triol, benzene-1,2,4-triol, chloroacetylation, benzene-1,2,3-triyl tris(2-chloroacetate), benzene-1,2,4-triyl tris(2-chloroacetate), sodium (2S,2R)-3-carboxy-2,3-dihydroxypropanoate; nucleophilic substitution; dimethylform

 
 
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