Please login first
Stereocontrolled preparation of substituted oxazolidin-2-one scaffold as the chiral building block for the synthesis of FTY720 analogues
, , *
1  Institute of Chemical Sciences, Department of Organic Chemistry, P. J. Šafárik University, Moyzesova 11, Košice, Slovak Republic

Abstract: An efficient strereocontrolled synthesis of substituted oxazolidin-2-one synthon 11 as the key intermediate in the synthesis of FTY720 analogues starting from the highly functionalized furanose scaffold 21 is reported.