Please login first
Ultrasonic irradiation as an energy source to catalyze the formation of a new bioactive sulfonylphthalimide
, * ,
1  Laboratory of Applied Organic Chemistry, Synthesis of Biomolecules and Molecular Modelling Group, Department of Chemistry, Sciences Faculty, Badji-Mokhtar-Annaba University, Box 12, 23000 Annaba, Algeria
Academic Editor: Juan Francisco García Martín


The use of ultrasonic irradiation as an energy source to catalyze the formation of new biomolecules represents an innovative approach in the field of organic synthesis and green chemistry. This method harnesses ultrasonic waves, high-frequency sound waves, to induce chemical reactions efficiently and rapidly.

When ultrasonic waves are applied to a chemical reaction, they generate pressure waves and local turbulence in the reaction medium. These extreme conditions promote the breaking of chemical bonds and the formation of reaction products at accelerated rates compared with conventional methods. Consequently, ultrasonic irradiation accelerates the synthesis process and enhances reaction yields.

In the specific case of forming a bioactive sulfonylphthalimide, using ultrasonic irradiation offers several advantages. Firstly, it reduces the reaction times required to obtain the desired product, contributing to an overall increase in synthesis efficiency. Additionally, the intensity of ultrasonic waves can be adjusted to selectively control the formation of specific products and minimize the generation of undesirable by-products. This technique can often be performed at room temperature or slightly elevated temperatures, avoiding the need for more energy-intensive reaction conditions.

Furthermore, ultrasound can facilitate the activation of reagents that are difficult to react under conventional conditions, making it an attractive technique in the fields of organic chemistry, especially in the synthesis of pharmaceutical and biologically relevant chemical compounds. This offers advantages such as improved productivity, energy savings, and the opportunity to explore new synthetic pathways in biology and industry.

Keywords: ultrasound irradiation; green chemistry; biomolecule; sulfonylphtalimide.