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Applications of Nanomaterials in Pediatrics
* 1 , 2 , 3 , 3
1  Faculty of Medicine, Department of Child Health and Diseases, Istanbul University, Istanbul, Turkey
2  Department of Food Processing, Technical Sciences Vocational School, Batman University, Batman, Turkey
3  Department of Nanotechnology, Institute of Science, Dicle University, Diyarbakir, Turkey
Academic Editor: Maryam Tabrizian

Abstract:

Nanotechnology could improve pediatrics. It could be used to tackle special pediatric medical difficulties, as typical medication delivery systems often lack selectivity, resulting in inferior outcomes and side effects. Nanotechnology can also be used to precisely deliver drugs to children's illness sites. Nanotechnology, such as targeted gene therapy, can help children with congenital and genetic illnesses.

Diagnostics in pediatrics can also be revolutionized through nanotechnology. Early and accurate diagnosis is crucial to prevent long-term complications and improve outcomes. Nanotechnology-enabled tools, such as nanoparticle-based imaging agents and biosensors, provide heightened sensitivity and specificity, allowing for early disease detection and precise monitoring. However, there are concerns about the safety and long-term effects of nanoparticles in children, whose developing bodies might react differently than those of adults. Ethical considerations of using advanced technologies in young populations also need careful attention.

Nanotechnology’s significance in pediatrics is profound, as it can help to address specific needs that distinguish children from adults. Pediatric patients’ ongoing growth and developmental stages present unique challenges. Nanoparticles ensure targeted drug delivery, improving therapeutic outcomes while minimizing side effects, which is crucial for conditions like pediatric cancers. Innovations in diagnostics brought by nanotechnology are equally significant, enabling early detection and timely interventions for better prognoses.

Another groundbreaking application is in vaccines. Nanoparticles can enhance vaccine safety and efficacy by ensuring targeted delivery and controlled release, which is particularly important for infants with developing immune systems. Nanotechnology also offers potential solutions for treating neurological conditions by bypassing the blood–brain barrier, a significant obstacle in drug delivery to the brain.

While nanotechnology promises vast improvements in pediatric medicine, it is essential to apply it safely and ethically. This overview highlights nanotechnology’s transformative potential in pediatrics, along with the challenges and considerations that must be addressed to ensure its safe and effective implementation.

Keywords: Pediatric patients; Nanoparticle-based imaging; Nanoparticles

 
 
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