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Microwave Synthesis of 4-Hydroxyquinazolines
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1  Departamento de Química Orgánica. Facultad de Ciencias. Universidad de Santiago de Compostela. Aptdo. 280. 27080-Lugo, Spain.

Abstract: Recently, we have reported [1] the microwave enhanced synthesis of 4-aminoquinazolines from anthranilonitrile and several aromatic nitriles Scheme 1. In the absence of another nitrile, anthranilonitrile dimerized to gave the corresponding 4-amino-2-(2'-aminophenyl)quinazoline. There we reported a reduction in reaction times together with an improvement in yields regarding to the methods using conventional heating.
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