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Synthesis of C-Glycosylated Amino Acids Suitable Building Blocks for the Synthesis of Glycopeptide Mimic
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1  University of Paderborn, Department of Organic Chemistry, 33095 Paderborn, Germany

Abstract: Glycopeptides are considered as a class of natural products which are responsible for a great variety of molecular recognition processes on the cellular surface including fertilization, pathogen-cell adhesion and the inflammatory response., It appears that the interactions of glycopeptides with their respective ligands is in general mediated by their carbohydrate epitopes. These glycosidic moieties exhibit a great diversity and very complex structures which makes their synthesis an almost arduous task.
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