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Coumarin-Chalcone Hybrids as new scaffolds in drug discovery
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1  Department of Organic Chemistry, Faculty of Pharmacy, University of Santiago de Compostela, 15782, Spain

Abstract: The first hydroxilated series of coumarin-chalcone derivatives has been synthesize starting from the corresponding salicyl aldehyde and β-ketoester precursors by a Knoevenagel reaction in order to obtain the methoxy derivatives which have been further hydrolyzed with a Lewis acid.
Keywords: Coumarin, Chalcone, Knoevenagel
Comments on this paper
Cheryl Cardenas
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