Introduction: Recurrent stroke contributes to the high global burden of stroke. Consequently, stroke secondary prevention has been considered a priority solution to reduce the global stroke burden. Stroke secondary prevention should include health education to encourage the adoption of healthy lifestyle behaviors. However, it is unclear which aspects of stroke knowledge should be addressed in these educational efforts. This study aims to identify whether knowledge variables about stroke are predictors of the adoption of healthy lifestyle behaviors post-stroke.

Methods: This is a cross-sectional study that included individuals post-stroke from a Brazilian metropolis using the Stroke RiskometerTM App. Binary logistic regression models (α=5%) were employed. Dependent variables included smoking, alcohol consumption, diet, physical activity, and the simultaneous adoption of four healthy behaviors. Independent variables included knowledge about what stroke is, its signs and symptoms, risk factors for its occurrence, and the individual's opinion that they may have a new stroke.

Results: A total of 75 individuals (63±13 years; 50% male) were included. The results demonstrated that having knowledge about the risk factors for stroke occurrence was a significant predictor for physical activity participation (B: 1.08, Odds Ratio (OR): 2.95, 95% Confidence Interval (95%CI): 1.03-8.41, p=0.043) and for the simultaneous adoption of four healthy behaviors (B: 1.45, OR: 4.27, 95%CI: 1.15-15.82, and p=0.030).

Conclusions: It is important to identify individuals who do not have knowledge about the risk factors for stroke and provide educational actions when the objective is to promote physical activity and the simultaneous adoption of all healthy lifestyle behaviors in secondary stroke prevention actions.