The object of the presented study is oysters (Crassostrea gigas, which is the main species of oyster consumed). The nutrition value of oysters is correlated to their longevity, which makes it interesting for both biology and food technology.

Oysters (Crassostrea gigas) were divided into two groups: a control group (normal conditions) and another in which the animals were additionally kept in a solution of hydrated fullerene C60 FWS for 24 hours (independent variables of the study).
After incubation, animals from both groups were kept in hypothermic conditions at 5±1°С without water for 10 days.

Samples of gill and mantle tissues were homogenized and the concentration of proteins, lipid peroxidation products (LPOs), the concentration of reduced glutathione (GSH), and the activity of superoxide dismutase (SOD) and catalase were determined.

It has been shown that the use of fullerene C60 at the stage of preparation of oysters for hypothermic storage increased the protective activity of the antioxidant system of molluscs against oxidative stress and anoxia. Thus, the formation and accumulation of LPOs after preliminary exposure of molluscs in seawater with the addition of fullerene C60 were lower compared to the control group. This may indicate both the effect of the neutralisation of reactive oxygen species by fullerene C60 and the activation of adaptive mechanisms in the protective activity of animal antioxidants.

This study of the protective activity of antioxidants in the tissues of molluscs of the experimental group showed that on the 9th day of storage, catalase activity and the concentration of GSH were significantly higher than in the control group.
This study showed that the pretreatment of animals with fullerene C60 affects the protective activity of the oyster antioxidant system compared to the control group and allows us to extend of the shelf life of oysters while maintaining organoleptic properties and physicochemical parameters.