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A review on perovskite magnetic nanoparticles (MNPs) used in magnetic hyperthermia (HT)
* 1 , 1 , 2, 3
1  School of Electrical and Mechanical Engineering Faculty of Science, Engineering and Technology (SET) The University of Adelaide, Adelaide, SA 5005, Australia
2  Department of Electrical and Computer Engineering, North Carolina State University, Raleigh, USA
3  Department of Materials Science and Engineering, North Carolina State University, Raleigh, USA
Academic Editor: Francesca Borgioli

Abstract:

Magnetic hyperthermia (MHT) has emerged as an innovative cancer treatment modality that involves the generation of heat by exposing magnetic nanoparticles (MNPs) to an alternating magnetic field (AMF). This approach has attracted considerable attention due to its ability to locally elevate the temperature of tumor tissues in a non-invasive manner. MHT can be used either as a standalone treatment or in combination with other therapeutic strategies, such as surgery, chemotherapy, or radiotherapy, enhancing the overall therapeutic outcome. Among the various magnetic materials available for hyperthermia applications, perovskites stand out due to their unique crystalline structure and versatile electronic and magnetic properties. These characteristics make perovskites promising candidates for developing highly efficient MNPs that can be fine-tuned to optimize heat generation under an AMF.

This review focuses on the magnetic properties of perovskite-based nanoparticles and their potential for use in MHT. The article discusses several perovskites that have been explored for hyperthermic applications, examining their structural, magnetic, and thermal properties. Additionally, the synthesis methods employed for fabricating perovskite-based MNPs are thoroughly reviewed. Despite the promising potential, challenges remain in harnessing the full capability of perovskites in MHT, including issues related to stability, biocompatibility, and scalability. These limitations are also addressed in this review, and future directions are proposed, ensuring the widespread adoption of perovskites as efficient and reliable MNPs for magnetic hyperthermia in clinical settings.

Keywords: Magnetic hyperthermia, Magnetic nanoparticles, perovskites, magnetic field
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