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Synthesis and anti-microbial screening of 3-(3,4-Dimethoxyphenyl)-1-(2-hydroxy-5- methylphenyl)prop-2-en-one and its heterocyclic analogs
Published: 01 November 2009 by MDPI in The 13th International Electronic Conference on Synthetic Organic Chemistry session Bioorganic Chemistry and Natural Products
Abstract: Chalcones and their heterocyclic analogues are known to possess a broad spectrum of biological effects. The present study is devoted to the synthesis of 3,4- Dimethoxy-2'-Hydroxy-5'-methyl chalcone and its derived products i.e. flavanone, flavonol, flavone, aurone, isoxazoline, chalconeimine and acetoxy chalcone. These newly synthesized compounds were screened for their antibacterial and anti-fungal activities.
Keywords: chalcone, heterocyclic analogs, anti-microbial activity screenings