Urban coastal areas face increasing flood risks due to climate change, sea level rise, and rapid urbanization. Traditional engineering solutions may not always be cost-effective, sufficient, or sustainable in addressing these complex and evolving challenges. As a result, Nature-based Solutions (NbSs) are gaining recognition as multi-functional approaches that work with natural systems to enhance coastal resilience and reduce vulnerability. This paper synthesizes current evidence and emerging approaches to implementing NbSs for flood risk management in urban coastal areas of the Nile Delta Region, drawing on interdisciplinary case studies, the scientific literature, and policy analyses. The study examines how NbSs contribute to flood mitigation while delivering a range of co-benefits, including improved environmental quality, enhanced urban planning, and strengthened community resilience. Additionally, NbSs offer long-term, adaptable, and cost-effective strategies that can complement traditional infrastructure. Key factors for successful implementation include inclusive stakeholder engagement, adaptive governance structures, and integrated planning across urban and ecological systems. However, barriers such as funding constraints, land use conflicts, limited technical capacity, and institutional fragmentation continue to hinder widespread adoption. This study presents a comprehensive framework to guide policymakers, urban planners, and practitioners in integrating NbSs into flood risk strategies. The findings emphasize the importance of context-specific, evidence-based, and inclusive approaches that align ecological functions with urban development goals, promoting more sustainable and resilient coastal urban futures.