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Use of Weissella cibaria BAL3C-5 B2 to produce functional breads enriched in vitamin B2 and fortified with dextran
1 , 1 , 2 , 2 , 3 , 4 , 5 , 3 , 4 , 4 , * 2 , * 1
1  Department of Biotechnology, Margarita Salas Center for Biological Research (CIB), CSIC, Madrid, 28040, Spain
2  Department of Biomedicine and Biotechnology, Institute of Functional Biology and Genomics (IBFG), CSIC-University of Salamanca, Salamanca, 37007, Spain
3  Biotechnology Department, AINIA, Paterna, 46980, Spain
4  Department of Food Biotechnology and Microbiology, Food Science Research Institute (CIAL), (CSIC-UAM), Madrid, 28049, Spain
5  Department of Applied Chemistry, Faculty of Chemistry, University of the Basque Country (EHU), San Sebastián, 20018, Spain
Academic Editor: Manuel Malfeito-Ferreira

Abstract:

Fermentation can improve the sensory, nutritional, and safety qualities of food. Furthermore, producing functional foods that contain bioactive compounds generated in situ by fermentative microorganisms is more sustainable than adding chemically or biotechnologically synthesized compounds.

Using optimized protocols for quantifying riboflavin (RF) and dextran, as well as gastrointestinal (GIDM) and colonic fermentation (CFDM) dynamic models, we have analyzed the functional properties of experimental breads (BLAB) made from doughs inoculated with Weissella cibaria BAL3C-5 B2, a RF-overproducing spontaneous mutant of the dextran-producing lactic acid bacteria (LAB) W. cibaria BAL3C-5, which was isolated from rye sourdough.

Doughs made with binary (50:50) flour mixtures (wheat/chickpea, wheat/quinoa, wheat/teff, rice/quinoa and buckwheat/quinoa) were fermented with or without (control) W. cibaria BAL3C-5 B2. Dextran (~2% w/w) was only detected in the LAB-fermented doughs, which had 2-3-fold higher vitamin B2 content. GIDM revealed that the bioaccessible vitamin B2 content in wheat/chickpea BLAB was ~3.7-fold higher than in control breads (BC). Using CFDM, buckwheat/quinoa BLAB and BC were shown to significantly induce SCFA production by the gut microbiota, although BLAB resulted in a greater increase (Lactobacillus and Bifidobacterium) or no decrease (Akkermansia) of the abundance of beneficial bacteria.

Keywords: Dextran; Functional foods; Lactic acid bacteria; Riboflavin
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