This report describes the case of a Mixed-breed dog brought to the teaching Veterinary Clinical Complex of the College of Veterinary Science & Animal Husbandry, Jabalpur, Madhya Pradesh. Based on clinical signs, a canine parvovirus type 2 (CPV-2) infection was diagnosed. A rectal swab sample was collected and the clinical diagnosis was confirmed by the positive results obtained by a commercially available rapid antigen testing kit (Ubio QuickVet CPV antigen testing kit. The prognosis of this disease depends on the virulence of the virus strain as well as the response of the organism to the treatment. However, it is also important that the treatment is started as soon as possible, because without it, the prognosis could be fatal. The necessary Antibiotic, Anti-diarrheal, Antacid, Anti-emetic, Vitamin B & C and fluids for restoring the fluid lost and the electrolyte imbalance, were administered in proper dosages according to the level of dehydration and body weight of the dog. The treatment regimen was continued for 6 days, and the pet owner was instructed not to give food and water for 6 days and the prognosis of dog was satisfactory. After six days of intensive supportive therapy, the dog showed marked clinical improvement with cessation of vomiting and hemorrhagic diarrhea. Hydration status, mucous membrane color, and appetite gradually normalized. The overall prognosis was satisfactory with complete recovery observed.