Photodynamic antimicrobial chemotherapy, a pathway for photo-inactivation of bacteria by porphyrins compounds

Fatemeh Fayyaz; Rahmatollah Rahimi; Mehdi Rassa; Reza Hedayat Yaghoobi

doi:10.3390/ecms-1-b003

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Photodynamic antimicrobial chemotherapy, a pathway for photo-inactivation of bacteria by porphyrins compounds

Fatemeh Fayyaz

^{*

1},

Rahmatollah Rahimi

¹,

Mehdi Rassa

²,

Reza Hedayat Yaghoobi

¹ Iran University of Science and Technology
² Department of Biology, Faculty of Science, University of Guilan , Rasht, Iran
³ Medical University of Kermanshah, Kermanshah, Iran

Published: 16 October 2015 by MDPI in 1st Electronic Conference on Molecular Science session Importance of Cell Death Pathways in Biology

https://doi.org/10.3390/ecms-1-b003

Abstract:

Photodynamic antimicrobial chemotherapy is a pathway for consideration of cell death of many microorganisms in biology such as bacteria. Various photo-sensitizer compounds were used in this technique such as porphyrin compounds. In this work, the effect of various concentrations of cationic porphyrin compounds was investigated and compared on cell death of S. aureus and E. coli by means of a 100 watt tungsten lamp.

Keywords: E. coli; Photobactericidal; Photodynamic antimicrobial chemotherapy; S. aureus; Tetra-cationic porphyrin.

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Fatemeh Fayyaz

Rahmatollah Rahimi

Mehdi Rassa

Reza Hedayat Yaghoobi