Reaction of substituted acetophenone (hepta-O-acetyl-b-maltosyl)thiosemicarbazones with ethyl bromoacetate was investigated. It’s indicated that the nature of solvents and the catalysts affected the reaction yields, and that the microwave-assisted heating method gave higher yields of products than the conventional heating one. Based on the optimum conditions, ionic liquid [HOCH2CH2NH3+]‒OAc, dried chloroform and microwave-assisted heating, the synthesis of some 2-iminothiazolidin-4-ones containg maltose moiety were synthesized. Their structure have been confirmed by spectral data (FTIR, 1H NMR, 13C NMR and MS).
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SYNTHESIS OF 2-AMINOTHIAZOLIDIN-4-ONES FROM (HEPTA-O-ACETYL-b-MALTOSYL)THIOSEMICARBAZONES OF SUBSTITUTED ACETOPHENONES
Published: 30 October 2015 by MDPI in The 19th International Electronic Conference on Synthetic Organic Chemistry session Ionic Liquids
Keywords: Ionic liquid, 2-Iminothiazolidin-4-one, β-Maltose, Microwave-assisted, Thiosemicarbazones