Nanoporous heterogeneous catalysts have been applied in many reactions due to the high contact area and orderly porous structures with thermal, chemical and mechanical stability . Pyrroles and their derivatives are one of the most important classes of heterocyclic compounds . A four-component coupling reaction (4cr) consisted of aldehydes 1, amines 2, 1, 3 -dicarbonyl compounds 3 and nitromethane 4 afforded substituted pyrroles 5, using MCM-41-SO3H as heterogeneous catalyst. We investigated the synthesis of pyrrole derivatives in the solvent-free conditions. Products were obtained in good yields and short times.
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Syntheses, Substitution and Cyclization Reactions of 7a,8,9,10,11a-Hexahydro-pyrido[3,2,1-jk]carbazoles With a Strychnos Alkaloids Partial StructureNext Article in session
MCM-41-SO3H as Heterogeneous Catalyst for One-pot Four Component Synthesis of Highly Substituted Pyrroles
Published: 01 November 2016 by MDPI in The 20th International Electronic Conference on Synthetic Organic Chemistry session Symposium on Microwave Assisted Synthesis
Keywords: Microwave, Pyrroles