Please login first
Synthesis and theoretical investigation of some new 4-substituted flavylium salts
* 1 , 2 , 3 , 2
1  Institute for Information Technologies Kragujevac, Department of Science, University of Kragujevac, Jovana Cvijica bb, 34000 Kragujevac, Serbia
2  Department of Chemical-Technological Sciences, State University of Novi Pazar, Vuka Karadžića bb, 36300 Novi Pazar, Serbia
3  Bioengineering Research and Development Center, Prvoslava Stojanovića 6, 34000 Kragujevac, Serbia


Synthetic flavylium salts possess the same basic structure as anthocyanins and their color and physical-chemical properties are notably dependent on the nature and position of the functional groups attached to the skeleton. Influence of position C-4 is very dominant in the stabilization of these molecules and the presence of substituent at that position is highly desirable for a food colorant because it would be stable over a wide range of pH values. Flavylium salts substituted at 4-position with bulky hydroxyphenyl substituents were synthesized by acidic condensation according to a slightly modified procedure described by Robinson and Walker. Their thermodynamic properties and conformational analysis have been studied at DFT level.

Keywords: flavylium salts, synthetic dyes, food colorants, DFT, conformational analysis