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Addition of Thiocyanic Acid to Chalcones: Practical Synthesis of 1,3-Diaryl-3-isothiocyanatopropan-1-ones
1 , 2 , * 1
1  N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky Ave., 119991 Moscow, Russian Federation
2  Department of Organic Chemistry, Moscow Technological University, 86 Vernadsky Avenue, 119571 Moscow, Russian Federation


Practical synthesis of 1,3-diaryl-substituted 3-isothiocyanatopropan-1-ones based on the reaction of chalcones with thiocyanic acid generated in situ by treatment of thiocyanate ammonium with dilute sulfuric acid has been developed.

Keywords: Chalcones; Isothiocyanates; Ketones; Thiocyanic acid; Addition