New multicomponent approach for the synthesis of coumarin derivatives by using environmental-friendly core/shell nanocatalyst

Ali Maleki; Parisa Ravaghi; Hamed Movahed; Morteza Aghaie

doi:10.3390/ecsoc-20-a034

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New multicomponent approach for the synthesis of coumarin derivatives by using environmental-friendly core/shell nanocatalyst

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¹ Catalysts and Organic Synthesis Research Laboratory, Department of Chemistry, Iran University of Science and Technology, Tehran 1684613114, Iran

Published: 01 November 2016 by MDPI in The 20th International Electronic Conference on Synthetic Organic Chemistry session General Organic Synthesis

https://doi.org/10.3390/ecsoc-20-a034

Abstract:

In this work, a three-component reaction of salicylaldehyde, diethylmalonate and phenylhydrazine in the presence of Fe₃O₄@SiO₂@NH₂as a core/shell nanocatalyst in EtOH was used to form a novel series of coumarin derivatives. This catalytic protocol was simply carried out in high yields and short reaction times. The remarkable magnetic properties of this nanocomposite provide easy separation of the catalyst from the reaction mixture without considerable loss of activity.

Keywords: Green chemistry, nanocatalyst, coumarin, salicylaldehyde, diethylmalonate, nanocomposite.

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