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New multicomponent approach for the synthesis of coumarin derivatives by using environmental-friendly core/shell nanocatalyst
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1  Catalysts and Organic Synthesis Research Laboratory, Department of Chemistry, Iran University of Science and Technology, Tehran 1684613114, Iran


In this work, a three-component reaction of salicylaldehyde, diethylmalonate and phenylhydrazine in the presence of Fe3O4@SiO2@NH2 as a core/shell nanocatalyst in EtOH was used to form a novel series of coumarin derivatives. This catalytic protocol was simply carried out in high yields and short reaction times. The remarkable magnetic properties of this nanocomposite provide easy separation of the catalyst from the reaction mixture without considerable loss of activity.

Keywords: Green chemistry, nanocatalyst, coumarin, salicylaldehyde, diethylmalonate, nanocomposite.