In this paper, we investigate the characteristics of optical chirality in multi-particles systems. In assembled multi-particles systems, optical chirality is present due to the different arrangements of the particles. The different arrangements results in the change of charge polarization in the nanostructures at left and right circular polarization. Polarization modes in the nanostructures are excited via different incident sources. The polarization modes interact between the nanostructures and results in different charge distributions, which change the circular dichroism (CD) properties of the whole systems. In this paper, we demonstrate the phenomenon through two case studies; One, changing the orientation of the incident light source, and two, changing the positions of the nanostructures. In the first case, the light source is incident onto a spiral chain of nanoparticles. Through different incident angles, we observed different absorption characteristics of the nanoparticle chain and this resulted in different CD properties at incident angle of 30 and 60 degree. This observation could be a huge advantage to obtain two CDs with single design. In the second case, we consider a dimer system. We have one nanoparticle moving in different positions and we observed that the CD of the dimer system has different characteristic compared to the normal system. Both case studies show us that the CD of the systems can be manipulates via external components. We also learn that via the changes at the external components, we can obtain two CD plots with single design. This further reduces the need to fabricate two chiral nanostructures to detect molecules with different secondary structures.