Polymer replication is critical to applications for microfluidics, especially for optofluidics. There's a huge discrepancy between processes used in academia and industry. Due to the limitation of cost and material properties, the PDMS casting is not suitable for large scale manufacture. In order to produce large numbers of devices by replicating a master structure, the micro-injection molding provides efficient and promising chips consist of rigid plastic, which is widely accepted in industry. In this talk, the challenging tooling and process control of micro-injection molding are addressed. Our advanced tooling, molding and welding technology can help customers transform the lab samples into marketable products rapidly.