Predict Nanoparticles (NP) toxicity is one of the biggest deal for both toxicologists and computational chemistries. The Nanodesk project is a SUDOE interreg project (Project Code: SOE1/P1/E0215) aimed at the development of an interactive and easy to use web-platform which will be help the plastic industry in the selection of the safer nanomaterials (NMs). The web-platform will implement a series of machine learning approaches which will be identify the safer NMs amongst a list selected by the industry and the scientific committee of the project. The project has started on July 2016 and will last for 36 month.