Synthesis of triols with C3 symmetry by ring opening of tris(oxiran-2-ylmethyl)-1,3,5-triazinane-2,4,6-trione with nucleophiles

M. Pilar Vázquez-Tato; Xesús Feás; Sandra Labandeira-Peteiro; Julio Seijas

doi:10.3390/ecsoc-15-00690

We are working on a new version of the website! To complete the upgrade, Sciforum will be unavailable on Saturday 18 July from 09:00 to 15:00 CEST. Thank you for your understanding.

Previous Article in event

Click reactions in the synthesis of tripodal 1H-1,2,3-triazol derivatives of 1,3,5-triazinane-2,4,6-trione

Previous Article in session

Microwave-assisted synthesis of new substituted anilides of quinaldic acid

Next Article in event

Structural studies of phenylhydrazine integration in carbohydrate derivatives

Next Article in session

Solvent-Free Microwaves Assisted Amination of Haloarenes by Aromatic Nucleophilic Substitution

Synthesis of triols with C3 symmetry by ring opening of tris(oxiran-2-ylmethyl)-1,3,5-triazinane-2,4,6-trione with nucleophiles

M. Pilar Vázquez-Tato

^*,

Xesús Feás

Sandra Labandeira-Peteiro

Julio A Seijas

¹ Department of Organic Chemistry. Facultade de Ciencias. Universidade de Santiago de Compostela. Aptdo. 280. 27080-Lugo. Spain

Published: 30 October 2011 by MDPI in The 15th International Electronic Conference on Synthetic Organic Chemistry session Microwave Assisted Synthesis

https://doi.org/10.3390/ecsoc-15-00690

Abstract: The reaction of tris(oxiran-2-ylmethyl)-1,3,5-triazinane-2,4,6-trione with phenol or N-methylaniline promoted by microwave heating, under solventless conditions, led to the opening of the oxirane ring through the less hindered carbon, leading to tripodal triols with C₃ symmetry in good yields.

Keywords: 1,3,5-triazinane-2,4,6-trione, microwave, oxirane, triol

View paper

81 Reads

M. Pilar Vázquez-Tato

Xesús Feás

Sandra Labandeira-Peteiro

Julio Seijas