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Synthesis of Triethylammonium 4-Aryl-3,5-dicyano-6-oxo-1,4,5,6-tetrahydropyridine-2-olates: 1-Cyanoacetyl-3,5-dimethylpyrazole as an Effective Alternative to Cyanoacetic Ester in Guareschi Reaction
* 1 , 2, 3
1  ChemEx Laboratory, Vladimir Dal’ East Ukrainian National University, kv Molodezhny 20-A 7/309, 91034 Lugansk
2  Chemical Diversity Research Institute, 2a-1 Rabochaya St., Khimki, Moscow region, 141400 Russia
3  Research Institute of Plastics, Perovsky proezd 35, 111024, Moscow, Russia

Abstract: Triethylammonium 4-aryl-3,5-dicyano-6-oxo-1,4,5,6-tetrahydropyridine-2-olates were obtained by reaction of (E)-3-aryl-2-cyanoacrylamides with 1-cyanoacetyl-3,5-dimethylpyrazole in the presence of 1.5 eq. of Et3N (20 °C, acetone) in 55-98% yields.
Keywords: Guareschi reaction, 1-cyanoacetyl-3,5-dimethylpyrazole