Previous Article in event
Next Article in event
Next Article in session
A new approach to 7-amino-4-oxo-4,5-dihydro-3H-pyrano[2,3-d]pyrimidine-6-carbonitriles
1
,
1
,
*
1, 2, 3
,
3
,
3
Published:
13 November 2020
by MDPI
in The 24th International Electronic Conference on Synthetic Organic Chemistry
session General Organic Synthesis
Abstract:
S-alkyl derivatives of thiobarbituric acid easily react with arylmethylene malononitriles in the presence of base to give new 7-amino-4-oxo-4,5-dihydro-3H-pyrano[2,3-d]pyrimidine-6-carbonitriles. The structure of products and the mechanism of formation are discussed.
Keywords: Thiobarbituric acid, malononitrile, 2-amino-4H-pyran-3-carbonitriles, Michael addition, heterocycliaztion
