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Microwave-assisted Asinger synthesis of thiazolines
Published:
14 November 2020
by MDPI
in The 24th International Electronic Conference on Synthetic Organic Chemistry
session General Organic Synthesis
Abstract:
An array of 2,4-disubstituted thiazolines was obtained through Asinger reaction approach from the straightforward treatment of diverse aldehydes/ketones with 1-mercaptopropan-2-one in presence of NH3 assisted by microwave irradiation displaying similar and sometimes higher yields as well as shorter reaction times that traditional Asinger rection conditions at room and lower temperatures.
Keywords: thiazoline; Asinger Reaction; microwave irradiation