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Synthesis of triphenylamine-imidazo[1,2-a]pyridine via Groebke-Blackburn-Bienaymé Reaction
Published: 14 November 2020 by MDPI in The 24th International Electronic Conference on Synthetic Organic Chemistry session General Organic Synthesis
A series of triphenylamine-imidazo[1,2-a]pyridine were synthesized in moderate yields (34-67%) by Groebke–Blackburn–Bienaymé reaction (GBBR) under eco-friendly conditions (20 mol% ammonium chloride catalyst in EtOH). Triphenylamine and imidazo[1,2-a]pyridines are a privileged core exhibited fluorescence and medicinal properties.
Keywords: Groebke–Blackburn–Bienaymé reaction; triphenylamine-imidazo[1,2-a]pyridine; fluorescence
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