MICROWAVE ASSISTED SYNTHESIS OF 2-ARYL BENZIMIDAZOLE

¹ Assistant Professor, Department of Pharmaceutical Chemistry, Konkan Gyanpeeth Rahul Dharkar College of Pharmacy & Research Institute, Karjat, University of Mumbai, Maharashtra, India
² Research Student, Hon’ble Loksevak Madhukarrao Chaudhari College of Pharmacy, Faizpur, Dist: Jalgaon; Maharashtra, India
³ Assistant Professor, Konkan Gyanpeeth Rahul Dharkar College of Pharmacy and Research Institute, Karjat, Dist-Raigad University of Mumbai
⁴ Principal & Professor, Konkan Gyanpeeth Rahul Dharkar College of Pharmacy and Research Institute, Karjat, Dist-Raigad University of Mumbai

Published: 19 November 2020 by MDPI in The 24th International Electronic Conference on Synthetic Organic Chemistry session Microwave Assisted Synthesis

https://doi.org/10.3390/ecsoc-24-08475

Abstract:

Various 2-aryl benzimidazole derivatives were synthesized using Microwave assisted reaction. The solvent and catalyst were selected to get product with good yield. From o-phenylenediamine and different substituted aromatic carboxylic acid using ethyl acetate as a catalyst derivative of 2-substituted benzimidazole were synthesized. All the synthesized compounds were screened by FTIR and 1H-NMR spectra.

Keywords: o-phenylenediamine; benzimidazole; Ethyl acetate; Aromatic carboxylic acid; Microwave assisted reaction

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