Self-isolation is a preventive measure that started in January 2020 as a response to the spread of the coronavirus COVID-19 infection, and it has no precedents in human history. During this pandemic, governments forced billions of people to self-isolate for several months, and the sanitary-hygienic assessment of self-isolation became an essential issue. It is possible to assess self-isolation using several methods:

We proposed a sanitary-hygienic definition of self-isolation.

We developed a hygienic self-isolation index point score (HSIPS) which determines that the optimal mode is directly proportional to the coefficients of a person’s physical activity (D), indoor area (air cubic capacity) per isolated (S), time spent in fresh air (T) and inversely proportional to the calorie intake.

The self-isolation index point score (HSIPS) determines if self-isolation is (1) optimal, (2) favorable, or (3) unfavorable.

We determined methods to assess the level of functional reserves of the body.

We identified the leading risk factors for the health of the self-isolation population.

We proposed sanitary-hygienic criteria for assessing self-isolation based on the sanitary-hygienic standards of the Russian Federation.

The sanitary-hygienic assessment of self-isolation can ensure the prevention of cardiovascular, alimentary-dependent diseases, and pathologies of the musculoskeletal system. Besides, self-isolation accompanies a decrease in motor activity and unbalanced nutrition.