3-(Biphenyl)acrylates are prepared in good yield by one pot Suzuki cross coupling - Wittig olefination reactions. Central building blocks are 4-formyl- and 3-formylphenylboronic acids and the stabilized (carbomethoxymethylidene)triphenylphosphorane. Examples of one pot Suzuki - double Wittig combinations are shown, also.
3-(Biphenyl)acrylates by one pot Suzuki cross coupling - Wittig olefination reactions
Published: 14 November 2020 by MDPI in The 24th International Electronic Conference on Synthetic Organic Chemistry session General Organic Synthesis
Keywords: Suzuki cross-coupling reaction, Wittig olefination, one pot synthesis