Design and Synthesis of a Photoaffinity Label for the Enzyme Tocopherol Cyclase

Wolf Woggon; Giovanni Fogliato; Giusep Derungs

doi:10.3390/ecsoc-2-01700

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Design and Synthesis of a Photoaffinity Label for the Enzyme Tocopherol Cyclase

Wolf D. Woggon

^*,

Giovanni Fogliato

Giusep Derungs

¹ Institut für Organische Chemie der Universität Basel, St. Johanns- Ring 19, CH-4056 Basel, Switzerland

Published: 01 November 1998 by MDPI in The 2nd International Electronic Conference on Synthetic Organic Chemistry session Medicinal and Bioorganic Application of Organic Synthesis

https://doi.org/10.3390/ecsoc-2-01700

Abstract: A mechanism based, photoaffinity labelled inhibitor of the enzym tocopherol cyclase was synthesized

Keywords: enzyme, reaction mechanism, photoaffinity label, tocopherol cyclase, transition state analogue

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Wolf Woggon

Giovanni Fogliato

Giusep Derungs