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STUDY ON REACTION OF SUBSTITUTED 4-METHYLQUINOLIN-2(1H)-ONES WITH SODIUM AZIDE
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Published:
03 November 2017
by MDPI
in The 21st International Electronic Conference on Synthetic Organic Chemistry
session Ionic Liquids
Abstract:
Reaction of different substituted 2-chloro-4-methylquinolines with sodium azide changed the direction to substituted tetrazolo[1,5-a]quinolines instead corresponding 2-azido-4-methylquinolines. Required 2-chloro-derivatives were obtained from substituted 4-methylquinolin-2(1H)-ones, which were synthesized by ring closing corresponding (un)substituted acetoacetanildes in the presence of ionic liquid [Bmim]OH. The structures of obtained compounds have been confirmed by using spectroscopic methods (IR, NMR and MS).
Keywords: Knorr synthesis, 4-methylquinolin-2(1H)-ones, ionic liquid, sodium azido.
