6th International Electronic Conference on Medicinal Chemistry
6th International Electronic Conference on Medicinal Chemistry
Part of the International Electronic Conference on Medicinal Chemistry series
1–30 November 2020
Medicinal Chemistry, drug discovery and development, Pharmacokinetics and pharmacodynamics, pharmaceutical science, Biosensors, Biological targets and biomarkers
- Go to the Sessions
- Event Details
Winner Announcement
On behalf of the chair of the 6th International Electronic Conference on Medicinal Chemistry (ECMC-6), we are pleased to announce the winners of the Conference Award:
Best Poster Award
- Adeyemi Rahman, Isabel Rozas, "Derivatives of Guanidine-Based DNA Minor Groove Binders as Antiprotozoal Agents".
Born in the United States and of Nigerian origin, I arrived in Ireland at a very young age. I completed my undergraduate degree in Medicinal Chemistry (2017) at University College Dublin. From my studies, I developed a great interest in drug discovery and development. Currently, I am in the final year of my Ph.D. at Trinity College Dublin under the supervision of Prof. Isabel Rozas. The main area of research of the Rozas group is framed within the medicinal chemistry field where we have focused on the development of potential anticancer, antipsychotic and anti-infective agents. My Ph.D. focuses on the design, synthesis and biological evaluation of guanidine-based derivatives as potential treatments for infectious diseases such as malaria, African sleeping sickness, leishmaniasis and Tuberculosis.
Best Presentation Award
- Valentina Barcherini et al., "Optimizing the Oxazoloisoindolinone Family: Identification and Biological Evaluation of a Potent and Selective Indole-Based p53 Activator in Human Colorectal Cancer".
Valentina Barcherini is a third-year Ph.D. student in Medicinal Chemistry in the group of Prof. Maria Santos at Faculty of Pharmacy of University of Lisbon. Valentina’s doctoral research is centered on the development of novel small molecules that act as p53-MDMs protein–protein interaction inhibitors to tackle cancer. Valentina holds a Master’s degree in Bioorganic Chemistry from the New University of Lisbon, Portugal. She graduated in Applied Chemistry from the University of Padova (Italy).
Best Oral Communication Award
- Mauro Ravera, Elisabetta Gabano, Domenico Osella "Dual- and Multi-Action Pt(IV) Antitumor Prodrugs or How to Kill Two bBirds with One Stone".
Professor Mauro Ravera is an Associate Professor of General and Inorganic Chemistry at the Department of Sciences and Technological Innovation of the Università del Piemonte Orientale in Alessandria (Italy).
Since the mid-1990s, together with Prof. Domenico Osella and more recently, with Prof. Elisabetta Gabano, both co-authors of the presentation, he has worked in the field of anticancer metallo-drugs, in particular platinum-based compounds. Moreover, part of the research of Mauro Ravera is devoted to the study of the redox properties of coordination compounds of biological interest with electrochemical techniques.
His decades-long research is summarized in more than 110 publications, which include research articles and review papers and over 180 conference abstracts and communications.
At the same time, we congratulate the Pascal Marchand and Thierry Besson teams for winning the prize of 1-day of hands-on/testing using microwaves offered by Microwave Technologies Consulting for “Synthesis of Potential Bioactive Benzo-, Pyrido- or Pyrazinothieno[3,2-d]pyrimidin- 4-amine Analogs of MPC-6827”. We would also like to congratulate the Laura Figuerola-Asencio team for being awarded the free 1-year ADMET Predictor® academic license offered by Simulations Plus sponsored by ADMET Predictor and the Ana Rita Neves team being awarded FREE ABSOLUTE CONFIGURATION BY VCD for "Lead optimization in the search for new antifouling compounds".
In addition, we congratulate the Camille Tisnerat and Amina Yusuf Jega teams for winning the Travel Awards of $250 offered by BioTools for “Synthesis and biological evaluation of new enantiopure 4-aminoalcohol-quinoline and -fluorene hybrids as antimalarial drugs” and “Identification of novel compounds from Neocarya macrophylla against toxins from Naja nigricollis using computational approach”, respectively.
Welcome from the Chair
On behalf of the MDPI journal Pharmaceuticals, it is my pleasure to invite you to participate to the 6th edition of our series of International Electronic Conferences on Medicinal Chemistry.
The event will occur online during the entire month of November 2020 and logging in as an author is now open. Our scientific committee welcomes posters, slideshows, as well as videos dedicated to all aspects of medicinal chemistry. You have many reasons to contribute to this conference: logging in is absolutely free of charge, and your work will be accessible to thousands of scientists from all over the world.
The most outstanding works, as elected by the scientific committee, will be rewarded with grants offered by the sponsoring journal Pharmaceuticals.
I hope to have the opportunity to virtually meet you as a contributor or a visitor in the future and I look forward to posting the results of your research in your preferred format.
Call for participations
The members of the scientific committee are pleased to announce the Call for Participations for the 6th International Electronic Conference on Medicinal Chemistry and to invite each researcher working in the exciting fields of medicinal chemistry and drug-related sciences to share her/his recent results with her/his colleagues around the world.
The conference will cover a wide range of aspects involved in drug discovery and development. A non exhaustive list of topics that will be considered comprises:
- ADMET
- Animal experimentation
- Assay development
- Biomarkers
- Biomolecules
- Biosensors
- Biotechnology
- Chemical synthesis
- Clinical studies and side effects reports
- Combinatorial chemistry
- Drug delivery (including bioconjugates and prodrugs)
- High throughput screening
- Hit identification
- Imaging techniques
- In silico experiments
- In vitro and in vivo studies
- Lead optimization
- Omics
- Pharmaceutical analysis
- Scale-up
- Structure–activity relationships
Participation to the 6th International Electronic Conference on Medicinal Chemistry is absolutely free of charge for contributors and visitors. Researchers are invited to provide a short abstract (250 words maximum without figure) on line at https://www.sciforum.net/login from now until October 28, 2019. Acceptance will be notified within a week after submission of the abstract. Then the author(s) will be asked to present their work (in English) in the form of a poster, a slideshow, or a video using the templates provided by the conference (see Instructions for Authors). All accepted submissions will be displayed online, at https://sciforum.net/conference/ECMC2020, on November 1-30, 2020.
Authors of the most outstanding contributions, as selected by the Scientific Committee, will be invited to publish their work as a research article free of charge or at a discounted price, in a Special Issue of the journal Pharmaceuticals.
The Scientific Committee looks forward to receiving contributions in response to this Call and will be glad to provide any further information to interested parties. Questions may be addressed to the chairman via e-mail at jean-jacques.vandeneynde@ex.umons.ac.be or to the Pharmaceuticals editorial office at ecmc@mdpi.com.
We thank you in advance for your attendance of this conference and look forward to a stimulating exchange.
Conference Chairs
Former Head of the Department of Organic Chemistry, University of Mons-UMONS, Belgium
Editor-in-Chief of Pharmaceuticals, Former Head of the Department of Organic Chemistry, University of Mons-UMONS, Belgium
Jean-Jacques.VANDENEYNDE@ex.umons.ac.be
Conference Committee
Normandie Univ, UNIROUEN, INSA Rouen, CNRS, COBRA UMR 6014, F-76000 Rouen, France
chemistry of heterocyclic compounds; microwave-assisted chemistry; kinases inhibitors; green chemistry applied to bioactive compounds; Alzheimer disease; Down syndrom; cancer
Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
biochemistry of and small molecule drug discovery for parasitic protozoa and helminths; 'neglected' tropical diseases; high-throughput and high content screening, and assay devlopment; point-of-care diagnostics; proteolysis
Faculté de Pharmacie, Université Libre de Bruxelles, Campus Plaine CP 205/5, 1050 Brussels, Belgium
medicinal chemistry; anticancer metal complexes; asymmetric synthesis
medicinal chemistry; drug design; cannabinoids; sugar-based surfactants
Dipartimento di Farmacia, Università degli Studi “G. d'Annunzio”, Chieti, Italy
aromatase inhibitors; bioactive compounds; small molecules; anticancer activity; medicinal chemistry; synthesis; drug discovery; PPAR agonists and antagonists; antiproliferative agents; nitric oxide synthase inhibitors
Department of Bioorganic Chemistry, Faculty of Chemistry, Wrocław University of Technology, Wrocław, Poland
medicinal chemistry; organic synthesis; biotransformations; enzyme inhibitors; organophosphonates; peptide mimetics; natural products in food
Foodborne Toxin Detection and Prevention Research Unit, Western Regional Research Center, USDA‐ARS, 800 Buchanan St., Albany, CA 94710, USA
antifungal agents; drug resistance; molecular medicine; redox molecules; signal transduction
Assistant Professor at the Department of Biomolecular Sciences, Section of Chemistry, School of Pharmacy, University of Urbino, Italy
medicinal chemistry; NMR; synthetic organic chemistry; anticancer drugs; melatonin; bisindoles; sugar-based surfactants; adenosine A2A receptor ligands; asymmentric synthesis; macrocycles; foldamers
Formerly professor at the Haute Ecole Provinciale de Hainaut-Condorcet, 7330 Saint-Ghislain, Belgium
medicinal chemistry; organic synthesis; parasitic diseases; orphan drugs
School of Pharmacy and Pharmaceutical Sciences, Trinity Biomedical Sciences Institute, Trinity College Dublin, 152−160 Pearse Street, Dublin 2 D02 R590, Ireland
anticancer drug design; breast cancer; novel antiestrogens; tubulin targeting agents; azetidinones, antiestrogen-drug conjugates; estrogen receptor; Burkitt's Lymphoma; Chronic Lymphocytic Leukaemia
Department of Life and Environmental Sciences, Unit of Pharmaceutical, Pharmacological and Nutraceutical Sciences Via Ospedale 72, I-09124 Cagliari, Italy
medicinal chemistry; enzyme inhibitors; heterocyclic compounds; antiproliferative agents
Università degli Studi di Cagliari, Dipartimento di Scienze Chimiche e Geologiche, Cittadella Universitaria, SS 554, bivio per Sestu, 09042, Monserrato (CA), Italy
peptide synthesis; peptide nucleic acid; indole synthesis; amide synthesis; mechanochemical reaction; borrowing hydrogen; microwave; heterocycle synthesis; hydroxamic acids
Faculty of Pharmacy, Universidade de Lisboa, Avenida Professor Gama Pinto, 1649-003 Lisboa, Portugal
organic synthesis; medicinal chemistry; heterocycles; anticancer drugs; p53 activators; NMDA receptor antagonists
Universidade Federal do Rio de Janeiro, IPPN, CCS, Bloco H-Ilha do Fundão, Rio de Janeiro, RJ-21941-902, Brazil
molecular modeling; computer-aided drug design; bioinformatics; chemoinformatics
Laboratório de Química Orgânica e Farmacêutica, Departamento de Ciências, Químicas, Faculdade de Farmácia, Universidade do Porto, Rua Jorge Viterbo Ferreira 228, 4050-313, Porto, Portugal,
Interdisciplinar de Investigação Marinha e Ambiental (CIIMAR/CIMAR), Universidade do Porto, Terminal de Cruzeiros do Porto de Leixões, Avenida General Norton de Matos, S/N 4450-208 Matosinhos, Portugal
medicinal chemistry; organic synthesis; heterocycles, P-glycoprotein; anticancer; anticoagulants; chiral drugs; marine natural products
Instructions for Authors
Authors should submit their work online by registering with www.sciforum.net and using the "Start New Submission" function once logged into the system.
Researchers interested in attending the conference must submit an abstract of the work they intend to present (maximum 250 words without figure, without reference), no later than 28 October 2020.
After the abstract is accepted by the Scientific Committee (1–5 days after receipt of the abstract), the authors will be invited to prepare a full description of their work in the form of a poster, slideshow, or video.
Posters must be uploaded as a PDF file using the Poster_template.pptx file available at the end of this section.
Slideshows must be uploaded as a PDF file using the PPT_template_file.pptx file available at the end of this section.
Oral communications must be uploaded as a mp4 file (video) using the PPT_template_file.pptx file available at the end of this section.
This must be uploaded before 30 October 2020, for a final check.
Contributions will be displayed on the website using Sciforum.net’s proprietary slides viewer and will be accessible at https://sciforum.net/conference/ECMC2020 at the time of the conference. They can be prepared in exactly the same way as for any traditional conference where research results can be presented. Contributions must be converted to PDF format before submission, so that they can be easily and automatically converted to be displayed online.
The organization of posters is left completely up to the authors, provided that they use the conference’s template.
We recommend the following organization for your slideshow or video:
Length of the presentation: no more than 30 slides
Slide 1 (strictly one slide): Title, authors’ names, affiliation(s), email address of corresponding author, logos of the laboratory and/or institution (not mandatory);
Slide 2 (strictly one slide): Graphical abstract; repeat the title of the presentation, but avoid other text as far as possible;
Slide 3 (strictly one slide): Abstract (max. 250 words) and 3–5 keywords, separated by semicolons;
Slide 4 and following slides: These should contain (in the given sequence) Introduction, Results and Discussion, Conclusions;
Last slide: Acknowledgments, and logos of sponsors (not mandatory).
List of Authors (997)
Event Awards
The following awards will be offered by our sponsors
The Awards
Number of Awards Available: 3
The open access peer-reviewed Journal Pharmaceuticals will offer one travel grant (500 CHF) to reward the best work in each session (poster, presentation, video). The best works will be selected by the members of the Scientific Committee.Number of Awards Available: 2
BioTools will offer two travel grants (2 X 250 US$) for female students. Selection will be made by the Company following strict scientific criteria.Number of Awards Available: 1
BioTools will offer one free absolute configuration determination using Vibrational Circular Dichroism (VCD). Selection will be made by the Company following strict scientific criteria.Number of Awards Available: 1
Microwave Technologies Consulting will offer a 1-day hands on/testing using microwaves (2.45 GHz and 915 MHz) in its lab in Lyon (France). Travel and lodging are at the expense of the awardee. Selection will be made by the Company following strict scientific criteria.Number of Awards Available: 1
Simulations Plus will offer one free 1-year ADMET Predictor academic license. Selection will be made by the Company following strict scientific criteria.Sponsors and Partners
Organizers
Sponsors
Exhibition Hall
Helping laboratories to achieve their goals and improve their workflow by providing them with the smartest possible solutions. That is what drives Analis. Thanks to its broad range of lab equipment and lab furniture, Analis can offer both global and integrated solutions in line with your needs. Whether pharma, life science, cell analysis, chemical, medical in vitro diagnosis and industrial QC/QA or R&D, its team of specialists injects its expertise into your applications. A level of professionalism that is also reflected in its after-sales service, application support, technical maintenance and follow-up in its daily quest to secure your satisfaction.
BioTools is known worldwide for instrumentation and lab services for characterization of chiral molecules. We specialize in determination of absolute configuration without crystallization using Vibrational Circular Dichroism (VCD). VCD provides fast and unambiguous results in solution for molecules with one or multiple chiral centers. VCD methodology is published in USP and has been used to solve over 8000 structures in the last decade. The determinations of AC with VCD have been published in all top medicinal / organic chemistry journals, submitted to US patent office and regulatory agencies.
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Hielscher Ultrasonics specializes in the design, development and production of ultrasonic devices - both for use in laboratories as well as for industrial applications. Due to the outstanding power of the ultrasonic processors and the high quality standards, Hielscher became the world's leading supplier of high performance ultrasonic equipment.
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The International Natural Product Sciences Taskforce (INPST) represents an open innovation platform bringing together scientists and key opinion leaders of the natural product scientific research field, as well as members of multiple scientific excellence centers and pharmaceutical-, biotech-, healthtech-, and natural product-related industries.
Linkam offer market leading solutions in hot stage and freeze-drying microscopy, optical DSC, and thermodynamic sample characterisation. We develop and manufacture a broad range of temperature and environmental control stages that help you to characterise materials including pharmaceutical compounds, polymer composites, biological tissue, fibres, nanomaterials, minerals, and metals. Add thermal sample control from high (1500°C) to cryo temperatures. There are also options for humidity, vacuum and pressure control as well gas purging and electrical connections.
Read more...Linkam stages are used with light microscopes and a wide range of analytical techniques including Raman, FTIR, WAX/SAX and many more to visualise and characterise the properties of materials. Each of our instruments are designed and manufactured in house by our team of highly experienced electrical, software and mechanical design engineers. Alongside our standard range we offer customised solutions, where we work very closely with the researcher to design, prototype and manufacture a bespoke system.
Microwave Technologies Consulting (MTC) specialises in research & process development, and equipment design using microwave (915 MHz, 2.45 GHz and 5.8 GHz) processing technology for applications in the field of biotech, food technology, nanotechnology, medical technology, and the chemical and pharmaceutical industries. The focus of MTC activity is to deliver customer-specific industrial solutions, technical, environmental, and economic process benefits. As an independent, scientifically unbiased, and commercially minded company, MTC is a reliable and trusted partner that connects academia and businesses to bring bright ideas and research into the marketplace and to bridge the gap between innovation and commercialization. We are dedicated to understanding and optimising microwave-assisted processes to enable timely process development in line with project demands, from basic R&D approach through to development and life-cycle management.
Human at the center of our culture & dreams.
Our mission is to develop the most advanced technological platform for predicting the impact of molecules (drug, endocrine disruptor, cosmetic, etc.) on the human body to better treat pathologies (orphan diseases, cancer, bacterial resistance, virus). Moreover, This platform is an alternative to useless animals model by combining new microfluidic technology , artificial intelligence and most advanced imaging techniques.
Our Vision: Our commitment to user and client satisfaction is the foundation for our success and the source of long-term value for our shareholders and employees.
A brief history in time: Founded in 1996, Simulations Plus employs over 80 employees and is publicly-traded on the NASDAQ stock exchange (ticker symbol = SLP). Our headquarters are based in Lancaster, California, with our pharmacometrics consulting team located in Buffalo, New York and our Quantitative Systems Toxicology team in Research Triangle Park, NC. Trusted distributors handle sales and scientific support in Asian territories. 19 of the top 20 pharmaceutical companies, plus numerous mid- and small-sized companies and all major regulatory agencies, license our modeling & simulation technology.
SMC is a pre-clinical CRO (Contract Research Organization) founded in 2014 with a mission to accelerate drug research and development through our focused fibrosis and inflammatory expertise.
We have supported over 700 pharmaceutical companies, bio-ventures and academics from over 30 countries with our cutting-edge research and pharmacology studies using our mouse models specialized for inflammation and fibrosis, including liver disease (NASH, NAFLD, Cirrhosis, HCC, ALF), IPF, CKD, IBD, SSc and cancer. In particular, our unique NASH-HCC model (STAMTM model) is a mouse model with high clinical correlation - 15 compounds tested in the model having progressed to clinical trials.
At SMC, we take pride in our ability to respond to the requirements of our clients. With our expertise in this field and experienced staff, we work closely with clients to design tailored studies that can generate high-quality results as quickly as possible.
LATOXAN produces and supplies Natural Active Ingredients aimed at Pharmaceutics, Animal Health & Nutrition, Cosmetics, Agriculture and Life Science Research. Since 1982, the company is the Expert in Venoms, toxins and plant metabolites chemistry. Venoms and venom peptides are sourced from our own venomous animals breeding facilities. Plant extracts and small molecules come from an exclusive partnership with a foreign academic Institution specialized in Plant Biochemistry and Pharmacology. Collaboration with several Research Organizations have enabled LATOXAN to expand its catalog to unique molecules and screening libraries.
LATOXAN is also involved in Drug Discovery Research projects on antimicrobials, pain-killing, haematology, cancerology, dermatology.
Pharmaceuticals (ISSN 1424-8247; CODEN: PHARH2) is a peer-reviewed open access journal of medicinal chemistry and related drug sciences, published monthly online by MDPI. The Swiss Chemical Society (SCS) and Academy of Pharmaceutical Sciences (APS) are partners of Pharmaceuticals and their members receive a discount on the article processing charge.
Reaction Biology Corporation is an industry leader and innovator specializing in assay services for early-stage drug discovery. Founded in 2001, Reaction Biology offers a wide range of services, including robust assay technologies for kinase and epigenetic biochemical and cell-based high throughput screening (HTS) and selectivity compound profiling. We also offer relevant HTS assay reagents, including highly purified and characterized epigenetic proteins. On average, several million HTS and profiling reactions are performed per year. Over 750 companies worldwide, including pharmaceutical, biotech, academic, and nonprofit laboratories, utilize our biochemical and cellular assay services and purchase epigenetic proteins.
A. Opening Session
Dear Participants, Dear Visitors,
D. General: Oral communications
E. Round Table on Natural Products
F. Round Table on Viral Infections
G. Round Table on Neurodegenerative Disorders
H. Round Table on Parasitic Diseases
I. Concluding Remarks
Dear Participants, Dear Visitors,
This 6th International Electronic Conference on Medicinal Chemistry is characterized by an impressive participation and an exceptional level of scientific quality. This success, we owe it to you! I just have to say "thank YOU".
We hope that we shall have the opportunity to virtually meet again next November on this platform, or ,hopefully, physically somewhere in the world.
Be careful and stay safe!
