Bio
Dr. Rafael Artuch (MD, PhD), has developed his career in Hospital Sant Joan de Déu and its associated research Institute, in Barcelona, Spain. In 1990 he got the degree in Medicine, in 1996 the title of specialist in Clinical Biochemistry and in 1998 the PhD title in Medicine about the biochemical basis of mitochondrial disorders. His career has been developed in the field of inborn errors of metabolism by studying the biochemical and molecular basis of these disorders, having remarkable experience in biomarker validation for both diagnosis and treatment monitoring and identification of new genes associated with human diseases with 300 indexed in PubMed. One of the main focus in his research is the biomedical aspects of Coenzyme Q10 deficiency. Dr. Artuch is coordinating a research program inside the scientific network CIBERER (program of metabolic and mitochondrial medicine) and in January 2022, he is the chairman of the Executive Committee of ERNDIM, the largest external quality control scheme program for laboratories working I the diagnosis of inborn errors of metabolism.

Bio
Dr. Salviati's research has focused on the molecular bases of neurometabolic disease, in particular mitochondrial disorders. His group is currently elucidating the genetics of the CoQ biosynthetic pathway in humans and the molecular bases of CoQ deficiency and of cytochrome c oxidase defeciency. He has co-authored over 130 articles published in international peer reviewed journals with a total IF over 800 and Hindex= 44. He has been awarded grants from both national and international institutions for a total of over € 2 M.

Bio
Dr. Hidalgo (PhD) is a Postdoctoral Researcher Fellow at Columbia University Irving Medical Center (CUIMC) of Columbia University (CU) in New York, where he studies the pathomechanisms and possible therapies of different kind of mitochondrial diseases, under the supervision of Dr. Michio Hirano. Dr. Hidalgo completed his biological studies at the Universidad de Granada (2014). After that, he obtained his Master degree and Ph.D. degree in Biomedicine (Cum Laude) at the Universidad de Granada (2020) under the supervision of Professor Luis Carlos Lopez. During his doctorate he studied a mitochondrial encephalopathy associated with Coenzyme Q deficiency and managed to completely reverse the pathological characteristics of the disease, using a new alternative therapy based on the bypass of the molecular defect. Besides, since 2015 he taught physiology in Medicine, Nursery and Physiotherapy bachelor degrees at the Universidad de Granada. He carried out several research stays at different international institutions, including the University of Nottingham, Utrecht University and Columbia University. During his career, he has obtained different fellowships and awards at a national and international level, such as from the Spanish Ministry or the European consortium, to develop his investigation. Actually, his scientific interest is to better understand the mitochondrial diseases focusing on the metabolism of mitochondrial DNA. For that purpose, he studies the effect of mutations in different proteins that are involved in the synthesis of nucleotides.

Bio
Dr. Iain P. Hargreaves has worked in the field of metabolic disease for 27 years and holds a Readership in clinical biochemistry at Liverpool John Moores University and an honorary consultant clinical science position at the Neurometabolic Unit, National Hospital, University College of London Hospitals, UK. He has published over 130 papers which cover coenzyme Q10 metabolism, mitochondrial dysfunction, oxidative stress and therapeutic strategies for treating mitochondrial disease. In addition, Dr. Hargreaves has published 2 books, the latter book, entitled ` mitochondrial respiratory chain disorders` will be used as a suggested reference for some of his proposed undergraduate/graduate student lectures. Within the UK, Dr. Hargreaves established the only coenzyme Q10 diagnostic service in 2000 and ran the biochemical mitochondrial disease service in London from 2009-2016 before he moved to Liverpool John Moores to begin full time lecturing and research. Dr. Hargreaves has presented his research work at a number of international meetings throughout Europe and the USA.