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Cancers Webinar | Kinases in Cancer and Other Diseases

17 Mar 2022, 16:00 (CET)

Diseases, Protein Kinases, Cancer, Therapy, Diagnostics, Inhibitors
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Welcome from the Chairs

5th Cancers Webinar

Kinases in Cancer and Other Diseases

Protein kinases are a big family of enzymes, which catalyze protein phosphorylation. The human genome contains 518 protein kinase genes. Phosphorylation is one of the major mechanisms for regulating various cellular processes, such as proliferation, apoptosis cell cycle, growth, apoptosis, differentiation, etc. Deregulation of kinase activity can result in striking changes in these processes. Furthermore, deregulated kinases are often found to be oncogenic and can be important for the survival and spreading of cancer cells. There are different ways for kinases to become involved in cancers: mis-regulated expression and/or amplification, mutation, chromosomal translocation, abnormal phosphorylation, and epigenetic regulation. Based on these assumptions there are a lot of variuos scientific projects assessing the importance of kinases in cancers as well as some other diseases, such as polycystic kidney disease, glomerulonephritis, neurodegeneration, retinal degeneration, lung inflammation and others. In clinical science the major two kinase investigation routes are using kinases as biomarkers in cancer prognostics and diagnostics as well treating cancers with kinase inhibitors and/or monoclonal antibodies. This webinar will provide us with some highlights on the new research achievements in those areas.

Date: 17 March 2022

Time: 4:00pm CET | 11:00am EDT | 11:00pm CST Asia

Webinar ID: 891 1874 7120

Webinar Secretariat: cancers.webinar@mdpi.com

Chair

Proteomics Centre, Institute of Biochemistry, Vilnius University Life Sciences Centre, Lithuania,
MAP Kinase Resource, Bioinformatics, Bern, Switzerland

DETAILS
Bio
2004 PhD in biochemistry, University of Basel, Switzerland 2011-2015 worked at Swiss Institute of Bioinformatics, CALIPHO group as biocurator-kinase expert 2017-2018 worked at Max F. Perutz Laboratories - University of Vienna Department of Microbiology, Immunology and Genetics as data scientist since 2018 works Proteomics Centre, Institute of Biochemistry, Vilnius University Life Sciences Centre as senior scientist and Vilnius Gediminas Technical University, Department of Chemistry and Bioengineering as asisstant professor ORCID: https://orcid.org/0000-0002-9365-1843

Invited Speakers

University of North Carolina, Chappel Hill School of Medicine, Derpartment of Pharmacology, United States

DETAILS
Bio
2004 PhD in biochemistry, University of Illinois, Urbana, IL, United States 1990-1994 worked at University of Washington, Seattle, WA United States as pharmacology postoc 1994-1995 worked at Department of Pharmacology, University of Washington, Seattle, WA as a lecturer since 1995 at Department of Pharmacology, Director of Graduate Studies, University of NC at Chapel Hill, NC, United States, since 2014 Professor, and Director of Graduate Studies ORCID: https://orcid.org/0000-0002-4736-9855

Pôle Chimie Balard Recherche, Institut des Biomolécules Max Mousseron (IBMM)-UMR5247, France

DETAILS
Bio
1997 PhD in Biology and Health Sciences at the University of Montpellier, France 1997-2000 worked at Scripps Research Institute, La Jolla, CA, United States Since 2000, at CNRS in Montpellier, France and CNRS Research Director since 2010 . She heads the Kinase Biosensor & Inhibitor group in the Cellular Pharmacology Team of IBMM (Institut des Biomolecules Max Mousseron) – Balard Chemistry Research Pole. and hasShe has also established a Mentoring Programme for Doctoral students of the Biology & Health Doctoral School of the University of Montpellier. ORCID: https://orcid.org/0000-0001-8106-9728

Webinar Content

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Program

Speaker/Presentation

Time in CET

Chair Dr. Jonas Cicenas

Chair Introduction

4.00 - 4.15 pm

Dr. Lee M. Graves

Affinity Profiling to Discover New Targets for Cancer Treatments

4.15 - 4.50 pm

Q&A Session

4.50 - 5.00 pm

Dr. May C. Morris

Fluorescent Peptide Biosensors for Probing Kinase Activities: Tools for Profiling Biomarker Signatures in Cancer Diagnostics

5.00 - 5.35 pm

Q&A Session

5.35 - 5.45 pm

Closing of Webinar

Chair Dr. Jonas Cicenas

5.45 - 5.55 pm

Relevant SI

Topical Collection "Kinases and Cancer"
Collection Editor: Dr. Jonas Cicenas

Kinases in Cancer and Other Diseases
Topic Editors: Dr. Jonas Cicenas & Dr. May C. Morris
Deadline for abstract submissions: 30 November 2022
Deadline for manuscript submissions: 28 February 2023

Sponsors and Partners

Organizers

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