5^th Cancers Webinar

Kinases in Cancer and Other Diseases

Protein kinases are a big family of enzymes, which catalyze protein phosphorylation. The human genome contains 518 protein kinase genes. Phosphorylation is one of the major mechanisms for regulating various cellular processes, such as proliferation, apoptosis cell cycle, growth, apoptosis, differentiation, etc. Deregulation of kinase activity can result in striking changes in these processes. Furthermore, deregulated kinases are often found to be oncogenic and can be important for the survival and spreading of cancer cells. There are different ways for kinases to become involved in cancers: mis-regulated expression and/or amplification, mutation, chromosomal translocation, abnormal phosphorylation, and epigenetic regulation. Based on these assumptions there are a lot of variuos scientific projects assessing the importance of kinases in cancers as well as some other diseases, such as polycystic kidney disease, glomerulonephritis, neurodegeneration, retinal degeneration, lung inflammation and others. In clinical science the major two kinase investigation routes are using kinases as biomarkers in cancer prognostics and diagnostics as well treating cancers with kinase inhibitors and/or monoclonal antibodies. This webinar will provide us with some highlights on the new research achievements in those areas.

Date: 17 March 2022

Time: 4:00pm CET | 11:00am EDT | 11:00pm CST Asia

Webinar ID: 891 1874 7120

Webinar Secretariat: cancers.webinar@mdpi.com