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Cells Webinar | Airway Smooth Muscle and Asthma

11 Nov 2022, 15:00 (CET)

Airway Smooth Muscle, Asthma, CONTRACTION, Proliferation, Migration
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Welcome from the Chair

21st Webinar on Cells

Airway Smooth Muscle and Asthma

This webinar is focused on airway smooth muscle biology and asthma pathogenesis, which is associated with the Special Issue ‘Airway Smooth Muscle and Asthma’. For this Special Issue, we invite authors to submit their original research articles and/or reviews reporting new developments in airway smooth muscle biology and asthma pathogenesis. Airway smooth muscle plays a multifaceted role in the physiological functions of the lung. Airway smooth muscle contracts and shortens in response to a wide range of endogenous and exogenous signals and, hence, represents the pivotal cell regulating bronchomotor tone, airway caliber, and ventilation distribution. Abnormal airway smooth muscle contraction is a key pathological process that induces airway hyperresponsiveness in asthma. Hence, inducing airway smooth muscle relaxation and inhibiting airway smooth muscle hyperreactivity are key strategies in controlling asthma attacks. Speaker 1, Dr. Penn, will provide us with the updated research on Biasing GPCR signaling in the airway as a therapeutic approach.

Although we know that airway smooth muscle plays an important role in regulating lung functions, there are many unanswered questions in this field. Speaker 2, Dr. Chun Seow, will give us updated research on the role of airway smooth muscle in regulating lung function.

Asthma is a heterogeneous lung disease with variable phenotypes (clinical presentations) and distinctive endotypes (mechanisms). It has been long thought that airway inflammation, particularly Th2 inflammation, is a driver of asthma pathogenesis. However, there is accumulating evidence to demonstrate that an inflammation-independent process also contributes to asthma pathogenesis. Speaker 3, Dr. Dale Tang, will provide us with the updated research on new developments of asthma pathogenesis, particularly focused on emerging mechanisms of asthma.

Date: 11 November 2022

Time: 3:00 pm CET | 6:00 am PST | 9:00 am EST | 10:00 pm CST Asia

Webinar ID: 881 0746 1503

Webinar Secretariat: cells.webinar@mdpi.com

Chair

Department of Molecular and Cellular Physiology, Albany Medical College, Albany, NY, USA

DETAILS
Bio
Dale D. Tang is Professor of the Department of Molecular and Cellular Physiology at Albany Medical College, New York, USA. He is Director of Cytoskeletal Signaling and Asthma Research Program at the school. Dr. Tang is an internationally recognized scientist on smooth muscle biology, cytoskeletal regulation of cell functions, and asthma pathogenesis. He is Editor-in-Chief of Respiratory Research, a leading journal in the area of respiratory medicine and research. He is also a member of the Editorial Board of Scientific Reports. His research has been funded by multiple NIH grants. He has published > 80 peer-reviewed articles in journals including iScience, Journal of Biological Chemistry, and Circulation Research. He has served on many NIH and American Heart Association study sections and review panels. He is a Fellow of the American Thoracic Society and a member of the American Physiological Society.

Invited Speakers

Department of Medicine, Center for Translational Medicine, Thomas Jefferson University, Philadelphia, PA, USA

DETAILS
Bio
Dr. Penn is Director of the Center for Translational Medicine, Thomas Jefferson University, Philadelphia, USA. He is also Professor of the Department of Medicine in the same university. Dr. Penn is a world-renowned scientist on G protein-coupled receptors (GPCRs), airway smooth muscle biology, and asthma pathology. He has published approximately 100 high-quality articles in highly recognized scientific journals. His research has been supported by multiple NIH grants and other agencies. He has served on many NIH study sections and grant review panels. He is a member of the American Physiological Society and Fellow of the American Thoracic Society.

Pathology and Laboratory Medicine, British Columbia University, Vancouver, BC, Canada

DETAILS
Bio
Dr. Chun Seow is Professor of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada. He is a well-recognized expert in the field of airway smooth muscle biophysics and lung functions. Dr. Seow received his BSc degree in Mechanical Engineering and PhD degree in Physiology from the University of Manitoba. He received his post-doctoral training in muscle mechanics at the University of Chicago. In 1996, he was recruited to UBC as a CIHR New Investigator (1996-2001) and CIHR/BC Lung Investigator (2001-2006). His research projects have been continuously funded by CIHR since 1996 without interruption. His research has also been supported by NSERC for the last 15 years. He is a member of the American Physiological Society, the Biophysical Society, the American Society of Mechanical Engineers, and a Fellow of the American Thoracic Society.

Registration

This is a FREE webinar. After registering, you will receive a confirmation email containing information on how to join the webinar. Registrations with academic institutional email addresses will be prioritized.

Certificates of attendance will be delivered to those who attend the live webinar.

Can’t attend? Register anyway and we’ll let you know when the recording is available to watch.

Webinar Content

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Program

Speaker/Presentation

Time in CET

Prof. Dr. Dale D. Tang

Chair Introduction

3:00 - 3:10 pm

Prof. Dr. Raymond Penn

Biasing GPCR Signaling in the Airway as a Therapeutic Approach

3:10 - 3:30 pm

Q&A

3:30 - 3:35 pm

Prof. Dr. Chun Seow

Airway Smooth Muscle and Its Role in Regulating Lung Function

3:35 - 3:55 pm

Q&A

3:55 - 4:00 pm

Prof. Dr. Dale D. Tang

Emerging Mechanisms of Asthma

4:00 - 4:20 pm

Q&A

4:20 - 4:25 pm

Closing of Webinar
Prof. Dr. Dale D. Tang

4:25 - 4:30 pm

Relevant SI

Airway Smooth Muscle and Asthma
Guest Editors: Prof. Dr. Dale D. Tang & Prof. Dr. Steven S. An
Deadline for manuscript submissions: 31 December 2022

Sponsors and Partners

Organizers

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