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Cells Webinar | Nervous System Development and Plasticity in Model Organisms III

4 May 2021, 17:00

Disease, Cells, Nervous System, Plasticity, Model Organisms
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Webinar Information

5th Webinar on Cells

Nervous System Development and Plasticity in Model Organisms III

The nervous system is essential for receiving, transferring, and processing information, which allows us to make important decisions and carry out everyday tasks. It is composed of two main cell populations, which are the neurons and the glial cells.
As the central part of the nervous system, neurons process incoming information and transmit it to different parts of the body. Glial cells provide support and protection for neurons and are necessary for neural development, synapse and myelin formation, and the proper functioning of neurons. They also maintain the homeostasis of the nervous system as some populations of glial cells can behave as neural stem cells during embryonic development and in adult stages.
During the development of an organism, the nervous system undergoes significant changes not only regarding its structure but also its function. Neurons, glial cells, and the numerous molecular signals and components that are part of the nervous system can play various roles during different stages of development and in different parts of the nervous system.
This webinar features several eminent experts in the field of nervous system development, maintenance, and regeneration in different model organisms.

Dr. Sepand Rastegar
Institute of Biological and Chemical Systems (IBCS),
Karlsruhe Institute of Technology (KIT),
Karlsruhe, Germany

Date: 4 May 2021

Time: 5:00 pm CEST

Webinar ID: 876 2960 1813

Webinar Secretariat:

Chair: Dr. Sepand Rastegar

The following experts will present and talk:

Dr. Sepand Rastegar, Institute of Biological and Chemical Systems (IBCS), Karlsruhe Institute of Technology (KIT), Germany

Dr. Sepand Rastegar studied Biology at the University of Strasbourg, France, where he obtained his diploma degree in 1996. Dr. Sepand Rastegar completed his PhD in the laboratory of Prof. Walter Knöchel at the University of Ulm, Germany. In 2000, Dr. Sepand Rastegar moved back to Strasbourg to do 2 years of post-doctoral research with Prof. Uwe Strähle at the IGBMC. In 2002, Dr. Sepand Rastegar obtained a permanent position at the French National Institute of Health and Medical Research (INSERM). In 2005, Dr. Sepand Rastegar moved to Germany to work at the Karlsruhe Institute of Technology (KIT). Currently, Dr. Sepand Rastegar is investigating the molecular mechanisms that regulate zebrafish neurogenesis and regeneration. His models are the embryonic spinal cord and the adult telencephalon. His full list of publications is available at

Dr. Nathalie Jurisch-Yaksi, Department of Clinical and Molecular Medicine, NTNU, Norway

Dr. Nathalie Jurisch-Yaksi’s research program is inspired by the multi-disciplinary expertise she has acquired during her scientific career. Dr. Jurisch-Yaksi first studied biology at the University of Lausanne in Switzerland. Later, she worked on transcription regulation and paracrine signaling involved in cell survival (PhD, DKFZ, Heidelberg, Germany), high-throughput drug screens and chemical biology to interfere with germ cell differentiation (postdoc, Harvard Medical School, USA), and cellular mechanisms of neurodegenerative diseases (postdoc, VIB-KU Leuven, Belgium). Since 2015, Dr. Jurisch-Yaksi has been leading her own team, first as a Senior Team Leader within the Yaksi Lab (Kavli Institute for Systems Neuroscience, NTNU, Norway), and since 2019, as a fully independent Group Leader at NTNU’s Department of Clinical and Molecular Medicine. Over the years, Dr. Jurisch-Yaksi’s team has developed a multidisciplinary approach combining state-of-the-art cellular and molecular biology, genetics, and system neuroscience tools with high-end microscopy and quantitative data analysis to study cell and organ physiology, fluid dynamics and animal behavior.

Dr. Christine Charvet, Center for Neuroscience, Delaware State University, United States

Christine Charvet is an Assistant Professor in the Center for Neuroscience at Delaware State University. Christine acquired her postdoctoral training in neuroimaging at Harvard Medical School and statistical genetics at Cornell University. Her research program leverages big data in genetics and neuroimaging to address fundamental questions in developmental and comparative neuroscience while providing practical applications to the biomedical community. For example, Christine and her colleagues developed a resource with which to find corresponding ages across humans and model organisms ( This resource is often used by researchers who study model organisms (e.g., mice) and need to translate their findings to humans. Christine is funded by the National Institute of Health and has published 33 articles in her field. Her appointment at Delaware State University is part of a cross-institutional NIH-funded effort to enhance the research infrastructure of Delaware and increase diversity in biomedical sciences.



Time in CEST

Dr. Sepand Rastegar

Chair Introduction

5:00 – 5:05 pm

Dr. Nathalie Jurisch-Yaksi

Diversity and Function of Motile Ciliated Cell Types Within Ependymal Lineages of the Zebrafish Brain

5:05 – 5:45 pm


5:45 – 6:00 pm

Dr. Christine Charvet

Integrating Neuroimaging With Transcriptomics Traces the Evolution of Development in the Human and Non-Human Primate Brain

6:00 – 6:40 pm


6:40 – 6:55 pm

Closing of Webinar
Dr. Sepand Rastegar

6:55 – 7:00 pm

Webinar Content

The fifth webinar of the MDPI journal Cells, entitled “Nervous System Development and Plasticity in Model Organisms III”, was held on Tuesday 4 May 2021. This online seminar was chaired by Dr. Sepand Rastegar (Karlsruhe Institute of Technology, Germany). Dr. Nathalie Jurisch-Yaksi (NTNU, Norway) and Dr. Christine Charvet (Delaware State University, United States) presented their research related to nervous system development and maintenance.

The first speaker to quick off this webinar was Dr. Nathalie Jurisch-Yaksi and her presentation addressed the diversity and function of motile ciliated cell types within ependymal lineages of the zebrafish brain. The second speaker was Dr. Christine Charvet and she showed how she integrates neuroimaging with transcriptomics to trace the evolution of development in the human and non-human primate brain. Both presentations were followed by a Q&A session, moderated by the chair, to answer the questions submitted by live online attendees.

The webinar was offered via Zoom and registration was required for attendance. The full recording can be found below.

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Relevant Special Issues

Neurogenesis and Regeneration in the Zebrafish Central Nervous System
Guest Editor: Dr. Sepand Rastegar
Guest Editor: Ms. Luisa Lübke
Deadline for manuscript submissions: 28 February 2022

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