Please login first

The 5th International Electronic Conference on Cancers

Part of the International Electronic Conference on Cancers (IECC) series
10–12 June 2026
Event's Timezone: Central European Summer Time
Abstract Submission Deadline
15 March 2026
Abstract Acceptance Notification
12 April 2026

Registration Deadline
7 June 2026

Tumor Microenvironment, Inflammation, Biomarkers, Theranostics, Artificial Intelligence, High-throughput-screening, Molecular Targeting, Cell Plasticity, Personalized Medicine
Bookmark
Bookmark event Remove event from bookmarks
Add this event to bookmarks
Event Registration Contact Us Become a Sponsor
Registrations are Open till 7th June 2026. Register for Free HERE.

We will notify you about your abstract presentation type by 31 May 2026 .
Please check your email frequently to avoid missing notifications. Thank you for your patience.

Welcome from the Chair

Dear colleagues,

On behalf of MDPI and Cancers, we would like to invite you to participate in the 5th International Electronic Conference on Cancers (IECC 2026) to be held from 10 to 12 June, 2026.

This conference aims to bring together researchers and experts from the wide range of basic to clinical fields of cancer research, academia, and biotech companies to discuss state-of-the-art findings and developments in cancer research, as well as the application of therapeutic strategies to explore further stages.

In this conference, the following sessions will be held:

Session 1. Cancer Stem Cells.
Session 2. Tumor Heterogeneity.
Session 3. Drug Resistance and Anti-cancer Drug Development and Screening.
Session 4. Cancer Survivorship and Quality of Life.
Session 5. Causes, Diagnosis and Treatment of Cancer.
Session 6. Patterns and Treatment Considerations of Childhood Cancer.
Session 7. Novel Methods and Technologies for Research and Treatment.

It is a must-attend conference for anyone interested in these subthemes.

We invite you to participate in this dynamic and interdisciplinary online forum by submitting abstracts for short talks related to the subthemes. IECC 2026 will provide you with a stimulating environment where you can present your research, engage in insightful discussions, and connect with fellow experts.

We look forward to welcoming you to IECC 2026.

Sincerely,

Laboratory of Cancer Stem Cell Engineering, Okayama University, Okayama, Japan

More News about MDPI Conferences

Program Overview

10th June
11th June
12th June
Morning - 9:00 AM CEST Morning - 9:00 AM CEST Morning - 9:00 AM CEST

Session 4.
Cancer Survivorship and Quality of Life

Session 1. Cancer Stem Cells


Session 7.
Novel Methods and Technologies for Research and Treatment


Flash Poster Session

Session 5.
Causes, Diagnosis and Treatment of Cancer

Afternoon - 14:00 PM CEST Afternoon - 14:00 PM CEST Afternoon - 14:00 PM CEST

Session 3.
Drug Resistance and Anti-cancer Drug Development and Screening

Session 7.
Novel Methods and Technologies for Research and Treatment

Session 2. Tumor Heterogeneity


Session 5.
Causes, Diagnosis and Treatment of Cancer

IECC 2026 Program (Day 1)

10th June - Morning

IECC 2026
Session 4. Cancer Survivorship and Quality of Life

Date: 10th June 2026 (Wednesday)
Time: 09:00 (CEST, Basel) | 03:00 (EDT, New York) | 15:00 (CST Asia, Beijing)

Time in CET Speaker Title
9:00-9:05 Prof. Dr. Masaharu Seno
Conference Chair
Opening Remark from Conference Chair
9:05-9:10 Prof. Dr. Sebastiano Mercadante
Session Chair

Welcome from the Session Chair
9:10-9:30 Prof. Dr. Kwok-Leung Cheung
Invited Speaker
Quality of life and psychosocial wellbeing in older women with primary breast cancer
9:30-9:50 Prof. Dr. Ahmed Elsayem
Invited Speaker
When less is Actually more, Goals of Care for Patients with Advanced Cancer
9:50-10:05 Laia Barrachina-Bonet
Selected Speaker
The role of the European Cancer Information System on pancreatic cancer surveillance
10:05-10:20 Ruichen Han
Selected Speaker
Decision-making patterns of adjuvant endocrine therapy among women with breast cancer: A qualitative study
10:20-10:35 Elsa Vitale
Selected Speaker
Influence of Heath Literacy on Quality of Life in oncology patients
10:35-10:50 Qiang Hu
Selected Speaker
The Impact of Mobile Health on the Quality of Life of Cancer Patients: An interventional study
10:50-11:05 Alexandru Roșu
Selected Speaker
Clinical outcomes of Sacituzumab Govitecan in metastatic breast cancer: evidence of survival and quality of life from a systematic review and meta analysis

10th June - Morning

IECC 2026
Session 1. Cancer Stem Cells

Date: 10th June 2026 (Wednesday)
Time: 11:05 (CEST, Basel) | 5:05 (EDT, New York) | 17:05 (CST Asia, Beijing)

Time in CET Speaker Title
11:05-11:10 Prof. Dr. Masaharu Seno
Prof. Dr. Angeliki Magklara
Session Chairs
Welcome from the Session Chair
11:10-11:25 Junyi Lin
Selected Speaker
Biomimetic Homotypic Nanoparticles Co-delivering Gemcitabine and IKKβ Inhibitor Reverse Gemcitabine induced Stemness for Enhanced Pancreatic Cancer Therapy
11:25-11:40 Gaia Giannitti
Selected Speaker

Dissecting the contribution of CD36 to extracellular vesicle–driven metabolic crosstalk between melanoma cells and adipocytes

10th June - Afternoon

IECC 2026
Session 3. Drug Resistance and Anti-cancer Drug Development and Screening

Date: 10th June 2026 (Wednesday)
Time: 14:00 (CEST, Basel) | 8:00 (EDT, New York) | 20:00 (CST Asia, Beijing)

Time in CET Speaker Title
14:00-14:05 Dr. Farrukh Aqil
Session Chair
Welcome from the Session Chair
14:05-14:20 Alaa Aboushanab
Selected Speaker
Synergistic Chemo-Immunomodulation via Nanocarrier Co-Delivery of Doxorubicin and Pexidartinib
14:20-14:35 Mariana Sousa
Selected Speaker

Functional reactivation of p53 as a promising therapeutic strategy in the treatment of ovarian cancer

14:35-14:50

Inês Mota
Selected Speaker

Combination of BBIT20 and Immunotherapy Enhances Antitumor Activity in Pancreatic Cancer

14:50-15:05 Ana Catarina Matos
Selected Speaker

Restoring therapeutic vulnerability in Multidrug-Resistant Ovarian Cancer with a first-in-class disruptor of the BRCA1–BARD1 interaction

15:05-15:20 SYLWIA AMMOUN
Selected Speaker

Cellular Prion Protein (PrPC) as a Therapeutic Target in Meningioma and Schwannoma Development and Multidrug Resistance

15:20-15:35

Wioletta Rozpędek-Kamińska
Selected Speaker

Selective PERK inhibition as a strategy to overcome hypoxia-induced survival in colorectal cancer cells

15:35-15:50

Alexander A. Shtil
Selected Speaker

Electrochemical Reduction of Copper (II) As a Potent and Versatile Approach for Tumor Cell Eradication

15:50-16:05

Martyna Natalia Muskała
Selected Speaker

Induction of apoptosis by extracts from transformed hairy roots of Plectranthus venteri in an in vitro cancer model

16:05-16:20

farnaz mohammadi
Selected Speaker

Targeting EPS8 by CRISPR/Cas9 Genome Editing Reduces Gemcitabine Resistance in Pancreatic Cancer Cells

16:20-16:40

Prof. Dr. Axel H. Schönthal
Invited Speaker

Development of Novel Drug Delivery Pathways Enabled by Perillyl Alcohol (NEO100), a Monoterpene with Multifaceted Biomedical Applications

IECC 2026 Program (Day 2)

11th June - Morning

IECC 2026
Session 7. Novel Methods and Technologies for Research and Treatment

Date: 11th June 2026 (Thursday)
Time: 09:00 (CEST, Basel) | 03:00 (EDT, New York) | 15:00 (CST Asia, Beijing)

Time in CET Speaker Title
9:00-9:05 Prof. Dr. Guomin Li
Session Chair
Welcome from the Session Chair
9:05-9:20 Olga Tselousova
Selected Speaker
CIRCULATING TUMOR DNA AS A BIOMARKER OF GENOMIC INSTABILITY AND CLONAL EVOLUTION IN BREAST CANCER
9:20-9:35 Ekaterina Lindunen
Selected Speaker
Bioinformatic Identification of ACTN4 as a Candidate Master Regulator of Local Invasion in Glioblastoma
9:35-9:50 Yuzhe Wang
Selected Speaker
A Novel CAM-Based Dual-Reporter Imaging Platform to Study Secretome-Driven Vascular Remodeling in Sarcoma
9:50-10:05 Michael Laurence Langsen
Selected Speaker
Validation and Clinical Translation of Non-Invasive Imaging Biomarkers for the Classification of Gliomas
10:05-10:20 Anna Shorina
Selected Speaker
Machine Learning-Based Association of Copy Number Alterations in a Mechanobiological Gene Panel with Metastatic Status Across Cancer Types
10:20-10:35 Olga Kamaeva
Selected Speaker
Investigation of the Protein Corona on Polyvinyl Alcohol-Stabilized Polymeric Nanoparticles
10:35-10:50 Elizaveta Kontareva
Selected Speaker
High-nitrogen artificial gas mixture-induced hypoxia decreases nanoparticle uptake in breast tumor cells with varying malignancy
10:50-11:05 Nikhil Gudivada
Selected Speaker
An analysis of RCTs using PARP inhibitors in the treatment of breast cancer
11:05-11:20 Maryem Mahfoud
Selected Speaker
Exploration of genes identified in antitumor resistance in triple-negative breast
11:20-11:35 Omar Hamad
Selected Speaker
Digital Pathology Approach to Mapping Collagen VI Tumor Spatial Arrangement in COVID-19 Tissue Slides Using ImageJ

11th June - Morning

IECC 2026
Session 7. Novel Methods and Technologies for Research and Treatment

Date: 11th June 2026 (Thursday)
Time: 14:00 (CEST, Basel) | 08:00 (EDT, New York) | 20:00 (CST Asia, Beijing)

Time in CET Speaker Title
14:00-14:05 Prof. Dr. Andrew A. Gumbs
Session Chair
Welcome from the Session Chair
14:05-14:25 Prof. Dr. Takeaki Ishizawa
Invited Speaker
Intraoperative fluorescence imaging for cancer surgery
14:25-14:45 Prof. Dr. Karol Rawicz-Pruszyński
Invited Speaker
AI in Gastric Cancer
14:45-15:00 Anastasia Frolova
Selected Speaker
A systematic LC-HRMS urinary metabolomics framework for identifying urothelial malignancy biomarkers within a comparative multi-cancer study
15:00-15:15 Taufeeque Ali
Selected Speaker
A Self-Amplifying Redox-Based Combination Therapy Using an ROS-Responsive Prodrug and Pharmacologic Ascorbate for Targeted Triple-Negative Breast Cancer Treatment
15:15-15:30 Nosimot Buhari
Selected Speaker
Comprehensive Computational Profiling of MSH3 Missense Mutations and Stability Effects in Cancers and Neurodegenerative Disorders
11th June - Afternoon
IECC 2026
Session 2. Tumor Heterogeneity

Date: 11th June 2026 (Thursday)
Time: 15:30 (CEST, Basel) | 9:30 (EDT, New York) | 21:30 (CST Asia, Beijing)

Time in CET Speaker Title
15:30-15:35 Prof. Dr. Henry H. Heng
Session Chair
Welcome from the Session Chair
15:35-16:05 Prof. Dr. Henry H. Heng
Keynote Speaker
Cancer as a Supersystem: Chromosomal Instability Drives Multiscale Heterogeneity Through Two-Phased Evolution
16:05-16:35 Prof. Dr. Jinsong Liu
Keynote Speaker
Polyploid Giant Cancer Cells as a Window into Tumor Heterogeneity
16:35-16:50 Paula De Juan-Maciá
Selected Speaker
The hypertrophic adipocyte niche fuels metabolic plasticity and invasive signaling in colorectal cancer
16:50-17:05 Fei Yang
Selected Speaker
Intratumoral Metabolic Heterogeneity Predicts Treatment Response in High-Risk Hodgkin Lymphoma: Evidence from the AHOD0831 Trial
17:05-17:20 Elena Filippova
Selected Speaker
SNHG6-centered RNA regulatory network links epithelial plasticity and apoptosis signaling in breast cancer
17:20-17:35 Fabrizio Fontana
Selected Speaker
Unraveling the role of extracellular vesicle-mediated interleukin-8 signaling in melanoma invasion

IECC 2026 Program (Day 3)

12th June - Morning

IECC 2026
Flash Poster Session

Date: 12th June 2026 (Friday)
Time: 09:00 (CEST, Basel) | 03:00 (EDT, New York) | 15:00 (CST Asia, Beijing)

Session
Poster Presenter
Title
Session 1
9:00-9:05 Olga Pershina
Selected Speaker
Age-related features of cancer stem cell and T-cell response to therapy in a lung cancer model in aged mice
Session 2
9:05-9:10 Alexey M. Burdennyy
Selected Speaker
Tumor-associated miR-124 and miR-137 in post-transcriptional regulation of ovarian cancer
9:10-9:15 Meryem Aarab
Selected Speaker
Phenotypic Heterogeneity of Circulating Tumor Cells in Lung Cancer Revealed by Immunocytochemical Profiling
9:15-9:20 Maria Francesca Fiorita
Selected Speaker
Adipocyte-Derived Conditioned Medium Influences the Malignant Phenotype of Human Breast Cancer-Associated Fibroblasts
Session 3
9:20-9:25 Mariarosa Fava
Selected Speaker
Lamotrigine Inhibits Breast Cancer Progression Through FoxO3a/TXNIP axis
9:25-9:30 Yueyang Zhang
Selected Speaker
Evaluation of Lobaplatin Chemosensitivity and Mechanistic Insights Using a 3D Bioprinted Primary Colorectal Cancer Model
9:30-9:35 Ye Yuan
Selected Speaker
Vimentin facilitates ubiquitination and degradation of NCOA4 to promote resistance to olaparib-induced ferroptosis in glioblastoma
9:35-9:40 Souandaou ATHOUMANI ALI
Selected Speaker
An RNA Sequencing approach for the identification of anticancer effects of Docetaxel in cervical cancer
Session 4
9:40-9:45 Ioannis Adamopoulos
Selected Speaker
Survival impact of surgery and radiotherapy in malignant phyllodes tumors: Meta-Analysis of cohort studies
9:45-9:50 Marzia Sichetti
Selected Speaker
MIND–BODY INTERVENTION FOR SYMPTOM MANAGEMENT IN BREAST CANCER SURVIVORSHIP: A FEASIBILITY QIGONG PILOT STUDY
Session 5
9:50-9:55 Linda Manna
Selected Speaker
Serum from Subjects with High Body Mass Index Modulates Multiple Myeloma Cell Phenotype
9:55-10:00 Ionela Codruta Bubuianu
Selected Speaker
Decoding Therapy-induced Senescence EVs: Proteomic and miRNomic Clues to NSCLC Chemoresistance
10:00-10:05 Erina Iwabuchi
Selected Speaker
Significance of HER2-related factor in HER2-low breast cancer
10:05-10:10 Lisa Elm
Selected Speaker
Distinct YAP-TEAD signaling states revealed by integrated mRNA and protein analysis in thymic epithelial neoplasms
Session 7
10:10-10:15 Sofia Kleimenova
Selected Speaker
Development of novel drug delivery systems based on extracellular vesicles and cell membranes for cancer therapy
10:15-10:20 Michaila Akathi Pantelaiou
Selected Speaker
Smart nanocarriers encapsulating chemotherapeutic agents
10:20-10:25 Daria Prilutskaya
Selected Speaker
Extracellular vesicles as a targeted drug delivery platform for cancer treatment
10:25-10:30 Anastasia Dubrovina
Selected Speaker
Development Omnipose Neural Network-Based Analytical Module for Morphometric Analysis of Metastatic Cancer Cells

12th June - Morning

IECC 2026
Session 5. Causes, Diagnosis and Treatment of Cancer

Date: 12th June 2026 (Friday)
Time: 10:30 (CEST, Basel) | 04:30 (EDT, New York) | 16:30 (CST Asia, Beijing)

Time in CET Speaker Title
10:30-10:45 Daniele Viavattene
Selected Speaker
Guilty by association: calcium-mediated apoptosis regulated at the ER by a newly discovered mTOR-STAT3 pathway
10:45-11:00 Wenyu Xue
Selected Speaker
Integrated Clinical and Functional Analysis Identifies miR-16-1-3p as an Active Passenger Strand Associated with Osteosarcoma Progression and Chemoresistance
11:00-11:15 Nemany A.N. Hanafy
Selected Speaker
Hyaluronic acid-functionalized CaCO₃ crystals as novel polyelectrolyte multilayer reservoirs for CPT-RB (Chemotherapy and Photodynamic therapy) targeting multiple myeloma
11:15-11:30 Ladislav Görög
Selected Speaker
Ratiometric TGF-β–MMP Biomarkers Capture Pathway Imbalance and Stratify Colorectal Cancer Progression
11:30-11:45 Imane SAIF
Selected Speaker
Evaluation of the epigenetic signatures of BRCA1 and TP53 as tools for metastatic prognosis: Translational study on a cohort of Moroccan women

12th June - Afternoon

IECC 2026
Session 5. Causes, Diagnosis and Treatment of Cancer

Date: 12th June 2026 (Friday)
Time: 14:00 (CEST, Basel) | 08:00 (EDT, New York) | 20:00 (CST Asia, Beijing)

Time in CET Speaker Title
14:00-14:05 Prof. Nicola Amodio
Session Chair
Welcome from the Session Chair
14:05-14:25 Dr. Enrica Antonia Martino
Invited Speaker
Diagnosis and treatment of Multiple Myeloma
14:25-14:40 Ilenia Valentino
Selected Speaker
MARCH5-Driven MFN2 Degradation Sustains Mitochondrial Fission and Drug Resistance in Multiple Myeloma
14:40-14:55 Valeria Abril Pelayo-Ramírez
Selected Speaker
In Silico Transcriptomic Identification of Recurrent Transmembrane Receptors Across 12 Major Cancers for Targeted Non-Viral Gene Therapy
14:55-15:10

Oloche Celestine Eije
Selected Speaker

Brain Cancer Gene Expression Analysis for Subtype Classification and Biomarker Discovery Using Machine Learning
15:10-15:25 Wei-Hsiung Yang
Selected Speaker
Transcription factor NR5A1 enhances wild-type p53 transactivation
15:25-15:40 Francesca Gualtieri
Selected Speaker
Heparan Sulfate-Mediated Mechanotransduction Promotes EMT and Aggressiveness in Ovarian Cancer
15:40-15:55 Kaoutar ANOUAR TADLAOUI
Selected Speaker
miR-200c and PRR11: A Diagnostic Duo in HPV-Driven Cervical Cancer—Unraveling Their Inverse Regulation for Early Detection
15:55-16:10 Elena Marusich
Selected Speaker
Iron Oxide Nanoparticles as Potential Agents for Combined Radiotherapy
16:10-16:25 Xiaoke Wang
Selected Speaker
Stem Cell Exhaustion Defines an Immunogenic Niche and a Circulating Biomarker for Nasopharyngeal Carcinoma
16:25-16:40 Xiaohong Li
Selected Speaker
Pralsetinib for RET Fusion-Positive Advanced Ascending Colon Cancer with Liver Metastasis: A Case Report and Literature Review

Abstract Book

Event Chair

Laboratory of Cancer Stem Cell Engineering, Faculty of Interdisciplinary Science and Engineering in Health Systems, Okayama University, Okayama, Japan Website

Introduction
Bio
Masaharu Seno graduated Osaka university in Japan and awarded Bachelor of Engineering in 1981. He worked for Takeda Chemical Industries, Ltd., Osaka, Japan as a Staff Scientist from 1981 to 1992. In this period, he was awarded Ph.D. on the thesis of fibroblast growth factor from Osaka University. Then, he moved to the Faculty of Engineering, Okayama University, Okayama, Japan engaged in protein engineering, nano-biotechnology and stem cell engineering including cancer stem cells from 1992 to 2022. From 1995 to 1996 and from 2000 to 2001, he stayed National Cancer Institute, NIH in the US as a guest scientist. Notably, he converted induced pluripotent stem cells into cancer stem cells in 2012 for the first time in the world. He was awarded Professor Emeritus from Okayama University in 2022 and is currently a professor of cancer stem cell engineering in the Faculty of Interdisciplinary Science and Engineering in Health Systems at the same university since 2022.

Session Chairs

Prof. Dr. Angeliki Magklara

1. Laboratory of Clinical Chemistry, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Greece; 2. Biomedical Research Institute, Foundation for Research and Technology-Hellas, Ioannina, Greece

Introduction
Bio
Professor Angeliki Magklara is a faculty member at the Faculty of Medicine, University of Ioannina, Greece, and Director of the Biochemistry (Clinical Chemistry) Laboratory at the University Hospital of Ioannina. Her research focuses on cancer biology, with particular emphasis on cancer stem cells, chemoresistance, and liquid biopsy biomarkers. By integrating multi-omics approaches, her research group investigates mechanisms of therapeutic resistance, especially in breast cancer. Prof. Magklara has authored numerous peer-reviewed publications, serves on international scientific review panels and journal editorial boards, and is actively involved in clinical diagnostics, medical education, and translational research initiatives.

Prof. Dr. Sebastiano Mercadante

Main Regional Center for Pain Relief & Palliative Care Unit, La Maddalena Cancer Center, Palermo, Italy

Introduction
Bio
Sebastiano Mercadante, born on 3rd December 1955, - Doctor's degree (Medicine & Surgery), 1973-1979 with full marks, 110/110 cum laude, University of Palermo. - Specialization in Anesthesiology (1980-1983), and Science of Nutrition (1984-1987), University of Palermo. - National abilitation for Full Professor of Anesthesiology, Intensive Care, and Pain Therapy - Director of Main regional center for Pain Relief & Palliative/Supportive Care Unit, La Maddalena, Palermo, Italy - Scientific Director, Regional home palliative care program SAMOT - More than 700 lectures at national and international congresses. - Associated Editor, editorial Board and/or referee of more than 40 international peer-reviewed journals in the field of pain and symptom management, palliative care, and anesthesiology - More than 500 papers published in peer-reviewed international journals, including Lancet, Lancet Oncol, J Clin Oncol, Ann Oncol, Eur J Oncol, Anesthesiology, J Pain Symptom Manage, Palliat Med. H-index = 89 (Google Scholar). - Author of more than 40 chapters and books. - Award Umberto Veronesi 2003 - Award of excellence in scientific research, American Academy of Hospice and palliative medicine, Boston 2010 - Award John Mendelson MD, University of Texas MD Anderson cancer center “for extraordinary contribution in palliative care” Houston, 11-12 October 2013. - Award for International Clinical Impact. EAPC Rotterdam June 2023 - Patent for “new delivery system for analgesics”. N.21596IT/EL/FG/EM - Since 1st December 2016, Adjunct professor of palliative medicine, MD Anderson, University of Texas, Houston, TX, USA - 2018-2021. Member of the national ministerial commission for pain and palliative care. - 2022-2021. First expert around the world on “cancer pain” and breakthrough pain” (expert.com) - Chair of “palliative care” subgroup of MASCC, since June 2024

Prof. Dr. Ajay Pratap Singh

Department of Cell and Molecular Biology, University of Mississippi Medical Center, Jackson, USA

Introduction
Bio
Dr. Ajay Singh is a tenured Professor of Cell and Molecular Biology and Vice Chair in the School of Medicine at the University of Mississippi Medical Center. He is also the Associate Director of Basic and Translational Research at the Cancer Center and Research Institute. His laboratory focuses on identifying novel tumor-associated genes and how they affect tumor cell behavior. His lab is also interested in understanding how tumor cells communicate with their surroundings to become more aggressive and therapy-resistant, and whether targeting these tumor-stromal interactions could be exploited for cancer prevention and therapy. Another focus is to understand molecular differences in tumors from patients of different racial and ethnic backgrounds and to investigate their roles in disparate clinical outcomes. He has published extensively, holds multiple US patents, and is a co-founder of a small Biotech company, Tatva Biosciences. He has received numerous honors and awards for his scientific and scholarly accomplishments and has received funding from major federal agencies, including NIH, DOD, and NSF, as well as from the state health departments and private foundations. He also actively serves on national and international grant study sections and is a member of the editorial boards of several scientific journals.

Prof. Dr. Henry H. Heng

Center for Molecular Medicine and Genomics, Pathology Department, Wayne State University School of Medicine, Detroit, MI, USA

Introduction
Bio

Dr. Farrukh Aqil

Department of Medicine, University of Louisville, Louisville, USA

Introduction
Bio
Farrukh Aqil, Ph.D., is an Associate Professor in the Department of Medicine and a member of the Brown Cancer Center at the University of Louisville. His research focuses on exosome-based delivery of small molecules and nucleic acids for cancer therapy, with particular emphasis on translational nanomedicine and targeted therapeutics. Dr. Aqil has authored more than 100 peer-reviewed publications and holds multiple U.S. patents. He is actively involved in mentoring graduate students, postdoctoral fellows, and junior investigators, and is committed to fostering collaborative research environments. He also serves on editorial boards of various journals, and as an ad hoc reviewer for NIH and NSF study sections.

Professor. Nicola Amodio

Department of Experimental and Clinical Medicine, University Magna Graecia of Catanzaro, Catanzaro, Italy

Introduction
Bio
Nicola Amodio earned a PhD in Molecular Oncology in 2007 and a specialization in Applied Pharmacology in 2011 at the University Magna Graecia of Catanzaro, Italy. He was a Postdoctoral Fellow at Memorial Sloan Kettering Cancer Center, New York, from 2006 to 2007. From 2008 to 2018, he worked as Research Fellow and Research Assistant at the University Magna Graecia of Catanzaro with support from AIRC, the Umberto Veronesi Foundation, and the Lilli Funaro Foundation. Since 2019 he has been a tenure track researcher, and since 2022 Associate Professor of Pathology at the same university. He has co-authored over 150 international publications, received awards from institutions including ASH and the Umberto Veronesi Foundation, and has been listed among the Top Italian Scientists by VIA Academy since 2019. He is Section Editor-in-Chief of Cancers. His research focuses on identifying novel therapeutic targets in cancer through integrated transcriptomic, epigenomic, and functional preclinical approaches.

Prof. Dr. Ewa Koscielniak

Medical Faculty, University of Tübingen, Tubingen, Germany

Introduction
Bio

Prof. Dr. Andrew A. Gumbs

1. Department of Minimally Invasive Digestive Surgery, Antoine-Béclère Hospital, Greater Paris University Hospitals, Clamart, France; 2. Department of Surgery, Otto von Guericke University Magdeburg, Magdeburg, Germany

Introduction
Bio
Professor Gumbs is the Director of Artificial Intelligence Surgery at the Hôpital Antoine Béclère, Assistance Publique-Hôpitaux de Paris. He is the Editor-in-Chief of Artificial Intelligence Surgery (aisjournal.net) and is the Chief Medical Officer of ACCREA Medical Robotics, which specializes in collaborative interventional robotics. He is also the President and founder of the Artificial Intelligence Organization for the Next generation of Surgeons (AIONS.ai). Professor of Surgery at Grigol Robakidze University and the University of Magdeburg, he was previously Director of the Minimally Invasive Hepatic-Pancreatic-Biliary Surgery Program at SMG-MD Anderson Cancer Center and prior to that the Director of Minimally Invasive Hepatobiliary Surgery and at Fox Chase Cancer Center in Philadelphia, Pennsylvania. He has been Instructor of Clinical Surgery at Cornell-Weill Medical College, Instructor of Clinical Surgery at Columbia University College of Physicians and Surgeons, and Assistant Professor of Surgery in the Department of Surgical Oncology at Fox Chase Cancer Center. He is certified in general surgery, hepatic-pancreatic and biliary surgery, robotic and in laparoscopic surgery. He has delivered local, regional, national, and international invited presentations primarily devoted to minimally invasive surgical techniques for the liver, pancreas, and digestive organs and artificial intelligence surgery. His articles have been published in Annals of Surgery, Surgery, Journal of the American College of Surgeons and the Proceedings of the National Academy of Science. He has volunteered for Doctors Without Borders in the Democratic Republic of the Congo and Haiti and has also done several humanitarian missions to Ecuador.

Prof. Dr. Guo-Min Li

Institute for Cancer Research, Chinese Institutes for Medical Research, Beijing, China

Introduction
Bio
Guo-Min Li is Director and Distinguished Investigator at the Chinese Institute for Cancer Research, CIMR, Beijing. He received his B.A. from Wuhan University and Ph.D. from Wayne State University. He trained with Nobel laureate Paul Modrich at Duke, discovering that DNA mismatch repair (MMR) defects cause cancer. Before returning to China in 2023, he held an endowed chair at UT Southwestern. His research links MMR to cancer and neurodegenerative diseases. He reconstituted human MMR in vitro, revealed epigenetic regulation, explained how MMR-deficient tumors respond to immunotherapy via activating the cGAS-STING pathway, and uncovered MMR’s role in driving DNA repeat expansion underlying neurodegeneration.

Committee Members

Department of Pharmaceutics, College of Pharmacy and Pharmaceutical Sciences, Florida A&M University, Tallahassee, USA

Department of Ophthalmology, University of Padova, Padova, Italy

Second Department of Surgery, Aretaieion Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece

ReGenera R&D International for Aging Intervention and San Babila, Clinic, Vitality Therapeutics, Milano, Italy

Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Pokfulam, Hong Kong

Department of Biochemistry and Molecular Biology, University of New Mexico, Albuquerque, USA

Department of Radiation Oncology, University of Michigan, Ann Arbor, USA

Department of Radiology Oncology, Centre De Haute Energie, Nice, France

School of Women’s & Children’s Health, University of New South Wales, Sydney, Australia

Department of Pathology and Experimental Cancer Research, Faculty of Medicine, Semmelweis University, Budapest, Hungary

Section of Hematology/Oncology, Children’s Hospital of Pittsburgh of UPMC, Pittsburgh, USA,
The Department of Microbiology and Molecular Genetics, The University of Pittsburgh School of Medicine, Pittsburgh, USA,
The Hillman Cancer Center, The University of Pittsburgh Medical Center, Pittsburgh, USA,
The University of Pittsburgh Liver Research Center, The University of Pittsburgh Medical Center, Pittsburgh, USA

Department of Life Sciences, Link Campus University, Rome, Italy

Department of Public Health Sciences, Sylvester Comprehensive Cancer Center, University of Miami School of Medicine, Miami, USA

Medical Oncology Department, Research Center Cancer Biology & Epigenetics Group and Clinical Trials Department, Institito Portugues de Oncologia do Porto (IPO-Porto), Porto, Portugal

Cancer League of Eastern Switzerland, Flurhofstrasse 7, St. Gallen, Switzerland

University of New Mexico Health Sciences Center, United States

Department of Pathology, New York University Grossman School of Medicine, New York, USA

Department of Immunology and Oncology, National Centre for Biotechnology (CNB-CSIC), Madrid, Spain

Department of Radiology and Imaging, University of Texas Medical Branch at Galveston, Galveston, USA

Nationwide Children’s Hospital Institute for Genomic Medicine and The Ohio State University College of Medicine Depts of Pathology and Pediatrics, Columbus, Ohio USA

Department of Medical Sciences, University of Aveiro, Aveiro, Portugal

Department of Pharmacy, University “G. d’Annunzio”, Chieti, Italy

Department of Biochemistry,Monash Biomedicine Discovery Institute, Monash University, Australia

Department of Radiology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China

Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, MD, USA

Keynote Speakers

Department of Anatomic Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX,USA

Introduction
Talk
Polyploid Giant Cancer Cells as a Window into Tumor Heterogeneity
Bio
Dr. Jinsong Liu received his PhD in Biochemistry from Case Western Reserve University and completed postdoctoral training at the Howard Hughes Medical Institute and the University of Michigan, followed by a pathology residency and surgical pathology fellowship at New York University. He joined MD Anderson Cancer Center in 1999. Over the past 26 years, Dr. Liu has been an active member of MD Anderson's world-renowned gynecologic diagnostic pathology team. He has authored more than 300 scientific publications in high-impact journals. Dr. Liu's laboratory made the unexpected discovery that polyploid giant cancer cells (PGCCs) — historically considered non-dividing or senescent — can dedifferentiate into blastomere-like pluripotent stem cell-like states, recapitulating early embryonic programs to generate drug-resistant and metastatic progeny. He chaired the inaugural International Conference on Polyploid Giant Cancer Cells in 2024, marking the formal establishment of this emerging field. His work provides a new conceptual framework for understanding cancer origin, therapeutic resistance, and their connections to fundamental developmental processes.

Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, MI,USA

Introduction
Talk
Cancer as a Supersystem: Chromosomal Instability Drives Multiscale Heterogeneity Through Two-Phased Evolution
Bio
Henry H.Q. Heng, PhD Professor of Molecular Medicine and Genetics and of Pathology Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, MI Dr. Heng received his PhD in Medical Genetics from the University of Toronto's Hospital for Sick Children, mentored by Dr. Lap-Chee Tsui, and completed postdoctoral training in chromosomal biology under Dr. Peter Moens at York University before joining Wayne State University School of Medicine in 1999. Over more than two decades of watching cancer evolution in action — tracing karyotype dynamics, transcriptomes, and phenotypes longitudinally through phase transitions — Dr. Heng developed the Genome Architecture Theory (GAT), a new information- and genome-based conceptual framework that fundamentally challenges the gene-centric paradigm of cancer research and evolutionary biology. Key contributions include the discovery of genome chaos, fuzzy inheritance, and two-phased cancer evolution — comprising a punctuated macroevolutionary phase dominated by genome chaos and a gradual microevolutionary phase dominated by gene mutation — a pattern commonly detected across all key transitions of cancer evolution, including transformation, metastasis, and drug resistance. Central to GAT is the concept of karyotype coding: the order of genes and genetic elements on chromosomes within the 3D genome constitutes a new layer of key genomic information, and system inheritance — defined by genome topology — represents the true blueprint of biological systems that organizes gene interaction networks. Dr. Heng's books, Genome Chaos: Rethinking Genetics, Evolution, and Molecular Medicine (Academic Press, 2019; 2nd ed. 2025) and Debating Cancer: The Paradox in Cancer Research, have attracted wide attention across the fields of cancer biology and evolutionary theory. He has authored over 200 peer-reviewed publications and serves on the editorial boards of seven international journals.

Invited Speakers

Department of Hepatobiliary-Pancreatic Surgery, Graduate School of Medicine, Osaka Metropolitan University, Osaka, Japan

Introduction
Talk
Intraoperative fluorescence imaging for cancer surgery
Bio
Professional Activities and Distinctions: Dr. Takeaki Ishizawa received his medical degree in 2000 from The University of Chiba, in Chiba Japan and then went on to complete his Ph.D. in 2008 at The University of Tokyo. In 2011, Dr. Ishizawa stayed in Paris as a fellow at the Institut Mutualiste Montsouris. Dr. Ishizawa performed more than 300 laparoscopic and open hepatobiliary and pancreatic surgeries at the Cancer Institute Hospital, Japanese Foundation for Cancer Research in Tokyo, between 2014 and 2017. Dr. Ishizawa had also participated in liver transplantation at the University of Tokyo Hospital. From April 2022, Dr. Ishizawa supervises hepatobiliary and pancreatic surgery using robot-assisted approach as a Professor of the Department of Hepatobiliary-Pancreatic Surgery at Osaka Metropolitan University. Areas of Research and Publication: Dr. Ishizawa has developed in vivo fluorescence imaging and actively applied these techniques to his clinical practices. So far, Dr. Ishizawa has been published for his work in hepatobiliary and pancreatic surgery and fluorescence-guided surgery in more than 80 peer-reviewed international journals, including the Gastroenterology and the Annals of Surgery. He also played a role as a president of the International Society for Fluorescence Guided Surgery (ISFGS, www.isfgs.org), aiming to share updated information on this topic among researchers, surgeons, and technicians. Dr. Ishizawa has been honored with many prestigious awards including: award from the 106th Annual Congress of Japan Surgical Society, the British Journal of Surgery Award at the 45th Congress of the European Society for Surgical Research, KARL STORZ Award at the 24th Annual Meeting of the Japan Society for Endoscopic Surgery, Best International Abstract Award at SAGES2016, and the 2017 International Guest Scholarship of American College of Surgeons.

Unit of Hematology, AO of Cosenza, Cosenza, Italy

Introduction
Talk
Diagnosis and treatment of Multiple Myeloma
Bio
Medical Doctor Day Hospital Department of Hematology – A.O. Annunziata - Cosenza with expertise in Diagnosis and treatment of lymphoproliferative disorders (Hodgkin and non Hodgkin lymphomas, multiple myeloma) Expert on Lymphoproliferative Disorders in Università della Calabria

Department of Molecular Microbiology & Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA

Introduction
Talk
Development of Novel Drug Delivery Pathways Enabled by Perillyl Alcohol (NEO100), a Monoterpene with Multifaceted Biomedical Applications
Bio
Axel H. Schönthal, PhD, is Associate Professor in the Department of Molecular Microbiology and Immunology at the Keck School of Medicine of the University of Southern California (USC) in Los Angeles. Before joining USC, he had obtained his PhD from the University of Karlsruhe, Germany, followed by a postdoctoral stay at the Cancer Center of the University of California in San Diego (UCSD), California. At USC, he pursues the development of novel anticancer agents and novel delivery methods to improve cancer therapeutic efficacy. As of 2026, he has authored over 200 scholarly articles and chapters with an H-Index of 54.

Emergency Medicine Department, University of Texas, MD Anderson Cancer Center, Houston, USA

Introduction
Talk
When less is Actually more, Goals of Care for Patients with Advanced Cancer
Bio
Ahmed Elsayem, MD, is a Professor of Emergency Medicine and Palliative Care at The University of Texas MD Anderson Cancer Center in Houston. He received his medical degree from University of Khartoum and completed his Internal Medicine residency at Howard University Hospital, followed by a clinical fellowship in Palliative Care at MD Anderson. He also completed public health training at the UT School of Public Health. Dr. Elsayem has over two decades of experience in palliative and emergency cancer care, with a research focus on outcomes among patients with advanced cancer presenting to the emergency department. His work centers on symptom burden, delirium, and prognostic factors for short-term mortality, aiming to improve early integration of palliative care in acute settings. He has held multiple leadership roles, including Director of the Acute Palliative Care Unit and Founder and Chair of the Acute Supportive Care Committee in Emergency Medicine. His contributions have helped shape clinical practice and research in oncologic emergency care and palliative medicine.

Department of Surgical Oncology, MUL Medical Center, Medical University of Lublin, Poland

Introduction
Talk
AI in Gastric Cancer
Bio
Karol Rawicz-Pruszyński, MD, PhD, is a Professor of Surgery, Surgeon-in-Chief of the Department of Surgical Oncology at University Clinical Hospital No. 1 in Lublin, and Vice-Dean of the Medical Faculty at the Medical University of Lublin, Poland. His clinical and academic expertise focuses on minimally invasive and robotic surgery, particularly in gastric, colorectal and hepatopancreatobiliary cancers, as well as hyperthermic intraperitoneal chemotherapy (HIPEC) and complex surgical oncology. He completed his medical degree, PhD, and habilitation at the Medical University of Lublin, Poland, with his scientific work centered on optimizing diagnostic and therapeutic pathways in advanced gastrointestinal cancers. In 2026, he was awarded the title of Professor by the President of the Republic of Poland. He has also completed international research fellowships at Erasmus MC in Rotterdam (the Netherlands) and The Ohio State University Wexner Medical Center in the United States. Professor Rawicz-Pruszyński is the Chairman of the Taskforce on Robotic Surgery and Artificial Intelligence at the Medical University of Lublin. His research output includes more than 85 scientific publications, an Impact Factor exceeding 335, and an h-index of 19. He has contributed to several national and international projects, including the GASTRODATA Registry and NCDB-based collaborations, with key publications in the fields of gastric cancer, textbook oncological outcomes, minimally invasive surgery and surgical oncology. In addition to his clinical and scientific work, he is actively involved in medical education, doctoral supervision, and editorial activities for international journals. His professional interests combine oncological surgery, robotic innovation, artificial intelligence, academic leadership, and translational research to improve outcomes for patients with gastrointestinal cancers.

School of Medicine, University of Nottingham, UK

Introduction
Talk
Quality of life and psychosocial wellbeing in older women with primary breast cancer
Bio
Kwok-Leung Cheung is Professor of Breast Surgery and Medical Education, and Deputy Head of Education and Director of The BMBS Medicine Programmes at the University of Nottingham, with clinical and research interests in breast cancer and geriatric oncology. He is the President-Elect of the International Society of Geriatric Oncology, a member of the Executive Committee of the European Society of Breast Cancer Specialists, and of the Breast Cancer Clinical Guidelines Committee and the Expert Adviser Panel of the National Institute for Health and Care Excellence. Professor Cheung pioneered the Symposium on Primary Breast Cancer in Older Women in the UK.

Registration


The registration for The 5th International Electronic Conference on Cancers will be free of charge! The registration includes attendance to all conference sessions.

If you are registering several people under the same registration, please do not use the same email address for each person, but their individual university email addresses. Thank you for your understanding.

Please note that the submission and registration are two separate parts. Only scholars who registered can receive a link to access the conference live streaming. The deadline for registration is 7 June 2026.

Instructions for Authors

Procedure for Submission
IECC 2026 will accept abstracts only. The accepted abstracts will be available online on Sciforum.net during and after the conference.

Important Deadlines
1. Deadline for abstract submission: 10 February 2026 15 March 2026.
2. Abstract acceptance notification:10 March 2026 12 April 2026.

Please note:
An abstract acceptance email only confirms that your abstract has been accepted. Oral or poster presentation invitations are determined separately by the conference chairs, and you will receive an additional email with the presentation result.

Abstract Submission
If you do not have an account, please register at www.sciforum.net. After logging in, submit your abstract using the Submit Abstract button on the conference homepage. No template is required.

Abstract Requirements
1. Types of Submissions
- Accepted: Original research abstracts; systematic reviews or meta-analyses abstracts (must comply with PRISMA 2020).
- Not accepted: Narrative, scoping, comparative, perspective, opinion, or essay-style reviews

2. Content Requirements
- Length: 250–300 words
- Structure: Introduction, Methods, Results, Conclusions
- Language: Clear, publication-ready English
- Originality: Must be original and unpublished; previously published abstracts will not be considered

3. Authorship
- The submitting author must ensure all co-authors approve the content.
- Authors may submit multiple abstracts, but only one abstract per author may be selected for an oral presentation.

Presentation Requirements

1. Each abstract must designate one presenter. To change the presenter, please contact us after you receive the oral/poster presentation invitation.
2. Only live presentations are accepted.
3. Presenters who do not attend the live session will not be eligible for awards or presentation certificates.

Oral Presentation and Slides Preparation

The slot for the oral presentation is 15 mins. We advise that your presentation lasts for a maximum of 12 mins, leaving at least 3 mins for the Q&A session.

Authors are encouraged to prepare presentations using PowerPoint or equivalent software for online display alongside their abstract. If provided, slides will be presented directly on the conference website via the Sciforum.net slide viewer and should be prepared in the same format as a traditional conference presentation of research results. All slides must be converted to PDF format prior to submission to ensure accurate online display.

Each presentation should:

- Communicate the research question or objective, methodology, key results, and scientific novelty;
- Use a clear and logical structure, typically Introduction-Methods-Results&Discussion structure (IMRaD) or a field-appropriate alternative;
- Emphasize the relevance of the work;
- Support key findings with clear figures or tables where appropriate;
- Conclude with a critical interpretation of the results and their impact.

Poster Presentation

Posters should be designed to allow independent understanding of the research and clearly present the essential elements of the study.

Each poster should include:

- Title, authors, affiliations, and contact details (clearly displayed at the top);
- Brief introduction outlining the research objective;
- Concise methodology summary;
- Main results, supported by clear, well-labeled figures or tables where appropriate;
- Short conclusion summarizing key findings and their relevance.

Technical specifications:
Dimensions (cm): 84.1 × 118.9 (A0 - portrait)
Resolution: 300 dpi
Pixel size (portrait, 300 dpi): 9933 × 14043 px
Minimum font size: ≥24

The poster template can be downloaded HERE. We will reach out to you closer to the dates of the conference with more information.

Note: The uploaded poster may be used as provided and serves as a reference. However, as long as the technical specifications are followed, scholars are welcome to use any poster template of their choice.

Potential Conflicts of Interest

It is the author's responsibility to identify and declare any personal circumstances or interests that may be perceived as inappropriately influencing the representation or interpretation of clinical research. If there is no conflict, please state "The authors declare no conflicts of interest." This should be conveyed in a separate "Conflict of Interest" statement preceding the "Acknowledgments" and "References" sections at the end of the manuscript. Any financial support for the study must be fully disclosed in the "Acknowledgments" section.

Copyright

MDPI, the publisher of the Sciforum.net platform, is an open access publisher. We believe authors should retain the copyright to their scholarly works. Hence, by submitting an abstract to this conference, you retain the copyright to the work, but you grant MDPI the non-exclusive right to publish this abstract online on the Sciforum.net platform. This means you can easily submit your full paper (with the abstract) to any scientific journal at a later stage and transfer the copyright to its publisher if required.

Publication Opportunities

1. Cancers Journal Publication
Participants in this conference are cordially invited to contribute a full manuscript to the conference's Special Issue published in Cancers (ISSN: 2072-6694 , Impact Factor 4.4), with a 20% discount on the publication fee. Conference discounts cannot be combined with reviewer vouchers. All submitted papers will undergo MDPI’s standard peer-review procedure. The abstracts should be cited and noted on the first page of the paper.

Special Issue Submission Deadline: 30 June 2027


2. Proceeding Paper Publication
Accepted abstracts will be included in the conference report of the 5th International Electronic Conference on Cancers, published in the Medical Sciences Forum (ISSN: 2673-9992). Authors of accepted abstracts are highly encouraged to submit an extended proceeding paper (ideally 4-8 pages in length) for free, please submit it to the same journal after the conference.

Proceedings paper submission deadline: 27 July 2026.

Please click HERE to submit your proceedings paper to Medical Sciences Forum, and be sure to disclose the conference information in your cover letter or mention the conference name in your submission.
IECC 2026_proceeding_paper-template.dot

Publication Notice: Proceedings papers will undergo peer-review procedure. Acceptance at the conference does not ensure final publication.


Manuscripts for the proceedings issue must be formatted as follows:
Title;
Full author names;
Affiliations (including full postal address) and authors' e-mail addresses;
Abstract;
Keywords;
Introduction;
Methods;
Results and Discussion;
Conclusions;
Acknowledgements;
References.

Event Awards

To acknowledge the support of the conference's esteemed authors and recognize their outstanding scientific accomplishments, we are pleased to announce that the conference will provide 6 awards including Best Oral Presentation Awards and Best Poster Awards.

The Awards
Best Oral Presentation Awards and Best Poster Awards

Number of Awards Available: 6

Best Oral Presentation Award

Eligibility: Open to all authors selected as oral speakers who have delivered their presentation. Failure to present, delegation of the presentation to another person, or use of AI-generated voice or similar substitutes will result in disqualification.
Criteria: Evaluation considers scientific rigor (clear, literature-supported research question or hypothesis, appropriate methodology, robust analysis and critical discussion of the results), IMRaD/field-appropriate structure, clarity of presented data (clear, well-labeled figures and tables), presentation skills and audience engagement, demonstrated scientific novelty and impact.
Prize: An award of CHF 200 and a certificate in recognition of your outstanding contribution.

Best Poster Award

Eligibility: Open to all authors who have presented their work through posters. Failure to present, delegation of the presentation to another person, or use of AI-generated voice or similar substitutes will result in disqualification.
Criteria: Evaluation considers scientific rigor (clear, literature-supported research question or hypothesis, appropriate methodology, robust analysis, and critical discussion of the results), IMRaD/field-appropriate structure enabling independent understanding, clarity of presented data (clear, well-labeled figures and tables), presentation skills (if orally presented), demonstrated scientific novelty and impact.
Prize: An award of CHF 200 and a certificate in recognition of your outstanding contribution.

There will be six winners selected for these awards. The winner will receive a certificate and 200 CHF each.

Winner Announcement: The award winners will be evaluated and selected by the scientific committee after the conference. Results will be announced on the website and all winners will be individually contacted via email.

Sponsors and Partners

For information regarding sponsorship and exhibition opportunities, please click here.

Organizers


Media Partners

Conference Secretariat

Ms. Ann Li
Mr. Russell Wang
Ms. Chloe Lv

Email:

For inquiries regarding submissions and sponsorship opportunities, please feel free to contact us.

Top