IJMS | Nitric Oxide: Physiology, Pharmacology, and Therapeutic Applications
Welcome from the Chair
17- 18 November 2020, VIRTUAL, Welcome from the Conference Chair
Nitric oxide (NO), a gaseous free radical, is one of the ten smallest molecules found in nature. Although toxic, it is recognized to be a gasotransmitter that plays multiple roles in normal physiology. NO regulates vascular relaxation, controls inflammation, and suppresses expression of pro-inflammatory mediators in mast cells, macrophages, vascular smooth muscles, affects metabolism, insulin resistance, and has a role in type-2 diabetes.
In this webinar, over a 2-day period, we will hear updates from some of the experts in this interesting, still evolving, and at time controversial field.
In 1992, the journal Science referred to NO as the “Molecule of the Year”. The important role that NO plays in human biology was recognized in 1998 when the Nobel Prize in Physiology and Medicine was awarded to Robert F. Furchgott, Louis J. Ignarro, and Ferid Murad for establishing NO as a messenger molecule. The past 30 years have been very fruitful in deciphering the role of NO in human physiology, with many questions still on the horizon.
We are pleased to sponsor this 2-day webinar on the various aspects of NO physiology, pharmacology, and therapeutic applications and would like to welcome all the participants.
This Webinar relates to the Special Issue Nitric Oxide: Physiology, Pharmacology, and Therapeutic Applications. Participants will have the opportunity to contribute with a manuscript to the special issue with a special discount of 20%.
Organized by Khosrow Kashfi, PhD, FRSC, FRSB
City University of New York School of Medicine, New York, USA
City College of New York, NY, USA
Graduate Program in Biology, CUNY Graduate Center, NY, USA
Date: 17-18 November 2020
Time: 14.30pm (CET) | 8.30am (EST)
Chair: Professor Khosrow Kashfi
Webinar ID: 999 0782 5213
Webinar secretariat: ijms.webinar@mdpi.com
Conference Chair
City University of New York School of Medicine, New York, USA•
City College of New York, NY, USA•
Graduate Program in Biology, CUNY Graduate Center, NY, USA
Keynote Speakers
Laboratory of Cancer Immunometabolism
Senior Investigator
Head, Molecular Mechanisms Section
Acting Deputy Chief
Center for Cancer Research
National Cancer Institute, Frederick, MD, USA
https://ccr.cancer.gov/Laboratory-of-Cancer-Immunometabolism/david-a-wink
Professor of Experimental Therapeutics University of Exeter Medical School Exeter, England
Speakers
Department of Biology, Tor Vergata University of Rome, Rome, Italy;
Redox Signaling and Oxidative Stress Group, Danish Cancer Society
Research Center, Copenhagen, Denmark
Discipline of Pathology, Lambe Institute for Translational Research,
School of Medicine, National University of Ireland
Galway, Ireland
Institute of Biomedicine of Seville (IBIS), IBiS/Hospital University “Virgen del
Rocío”/CSIC/University of Seville, Seville, Spain
Redox Signaling and Oxidative Stress group
Danish Cancer Society Research Center
Copenhagen, Denmark
Department of Pharmacology, Ribeirao Preto Medical School,
University of São Paulo, SP, Brazil
Principal Investigator, Vascular Medicine Institute,
Co-Director, Center for Metabolism and Mitochondrial Medicine,
University of Pittsburgh School of Medicine,
Pittsburgh, PA, USA•
Editor, Nitric Oxide
Departments of Chemistry and Biology
The College of Staten Island
City University of New York, NY, USA
PhD Student
Department of Cancer Biology
College of Medicine & Life Sciences
The University of Toledo, Toledo, OH, USA
Director of Endocrine Physiology Research Center
Research Institute for Endocrine Sciences,
Shahid Beheshti University of Medical Sciences, Tehran, Iran
School of Pharmacy and Biomolecular Sciences,
University of Brighton, Centre for Stress and Age-related Disease,
Moulsecoomb, Brighton, England
Unit of Molecular Metabolism, Department of Clinical Sciences
Lund University, Malmö, Sweden
Department of Pharmacology & Chemical Biology
University of Pittsburgh School of Medicine,
Pittsburgh, PA, USA
Center for Vascular Biology Research
Beth Israel Deaconess Medical Center
Harvard Medical School,
Boston, MA, USA
Department of Medicinal Chemistry and Pharmacognosy,
College of Pharmacy,
University of Illinois at Chicago,
Chicago, Illinois, USA
The Solomon H. Snyder Department of Neuroscience
Johns Hopkins University School of Medicine
Baltimore, MD, USA
Webinar Content
On Tuesday and Wednesday, 17/18 November 2020, MDPI and IJMS organized the first virtual conference on IJMS, entitled: “Nitric Oxide: Physiology, Pharmacology, and Therapeutic Applications"
The introduction was held on both days by the chair of the webinar, Dr. Khosrow Kashfi. Dr. Khosrow Kashfi is an Associate Medical Professor of Pharmacology at the City University of New York School of Medicine, a 7-year BS-MD program that is focused on producing broadly-educated, highly-skilled medical practitioners to provide quality health services to communities historically underserved by primary care practitioners.
The webinar was offered via Zoom and required registration to attend. The full recording can be found here on Sciforum website. In order to stay updated on the next webinars on IJMS, be sure to sign up for our newsletter by clicking on “Subscribe” at the top of the page.
Day 1:
Day 2:Program 17 November: Day 1: NO in cancer, cardiovascular, and the immune system
| Speakers/Presentations | Time EST | Time CET |
|
Khosrow Kashfi Opening Remarks |
8:30am | 2.30pm |
|
David A. Wink Keynote Speaker |
9:00am | 3.00pm |
|
Giuseppe Filomeni Redox activation of ATM modulates S-nitrosylation and mitophagy: effects on immune cell activation |
10:00am | 4.00pm |
|
Sharon Glynn Influence of nitric oxide on prostate cancer initiation and progression |
10:25am | 4.25pm |
|
Melanie Flint
|
10:50am | 4.50pm |
|
Salvatore Rizza Exploiting S-nitrosylation for cancer therapy: facts and perspectives |
11:15am | 5.15pm |
|
Asghar Ghasemi Nitrate and nitrite for management of type 2 diabetes: Translation from |
11:40am | 5.40pm |
|
Sruti Shiva Nitrite activates PKA to regulate cardiomyocyte function |
12:05pm | 6.05pm |
|
Probal Banerjee Exploiting the Diverse Roles of Nitric Oxide Synthase Isozymes |
12:30pm | 6.30pm |
|
Roshale Fernando Normalizing arginine metabolism in tumor associated macrophages: A novel immunotherapeutic strategy for breast cancer |
12:55pm | 6.55pm |
Program 18 November: Day 2: NO in metabolic syndrome, insulin resistance, type-2 diabetes, and beyond
-
| Speakers/Presentations | Time EST | Time CET |
|
Khosrow Kashfi Opening Remarks |
08:30am | 14.30pm |
|
Thiago Cunha NO signaling mediates peripheral analgesia |
09:00am | 15.00pm |
|
Jordi Muntané Relevance of NO downregulation during the treatment of liver cancer with Sorafenib |
09:25am | 15.25pm |
|
Sevda Gheibi Hydrogen sulfide potentiates the favorable metabolic profile of inorganic nitrite in type 2 diabetes |
09:50am | 15.50pm |
|
Carola Neumann Nitroalkenes and cancer: an update on anti-cancer drug development efforts |
10:15am | 16.15pm |
|
Break |
10.40am | 16.40pm |
|
Dipak Panigrahy
|
10:55am | 16.55pm |
|
Douglas Thomas Nitric oxide; the new architect of epigenetic landscapes |
11:20am | 17.20pm |
|
Bindu D. Paul Role of nitrosylation and sulfhydration in aging and neurodegeneration |
11:45am | 17.45pm |
|
Khosrow Kashfi NOSH-aspirin (NBS-1120), a multitarget inhibitor for the treatment of |
12:10pm | 18.10pm |
Relevant Special Issue
Special Issues in IJMS
Nitric Oxide: Physiology, Pharmacology, and Therapeutic Applications
Guest Editor: Prof. Dr. Khosrow Kashfi
Deadline for manuscript submissions: 30 April 2021.
Endogenous Gaseous Signaling Molecules: Their Mechanism(s) of Action and Pharmacological Effects
Guest Editor: Dr. Marcin Magierowski, Prof. Dr. Binghe Wang
Deadline for manuscript submissions: 30 April 2021
Sponsors and Partners
Organizers
