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Molecules Webinar | Advances on Bioanalysis: Recent Approaches in the Determination of Biomarkers, Drugs of Abuse and Medicines

27 Jul 2021, 15:00

Bioanalysis, Biomarkers, Drugs of Abuse, Medicines
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Welcome from the Chairs

14th Molecules Webinar

Advances in Bioanalysis: Recent Approaches in the Determination of Biomarkers, Drugs of Abuse and Medicines

Analytical tools to determine drugs, drugs of abuse or biomarkers, either to assess human exposure to those substances or to diagnose diseases, are mandatory for every laboratory working in the bioanalytical field. The development of highly sensitive analytical technology (e.g., time of flight and high-resolution or Orbitrap mass spectrometers) has allowed us to widen the scope of the applications of such techniques to other areas—for instance, the development of new therapeutic agents and industry.

This progress concerning instrumentation was accompanied by important achievements related to sample preparation approaches, trending in low-sample, low-cost, and low-organic solvent procedures without compromising sensitivity and allowing for the analysis of alternative samples, such as exhaled breath, hair, oral fluid, or sweat.

Renowned scientists of the area will present interesting applications of these technologies in this webinar.

The related Special Issue Advances on Bioanalysis: Recent Approaches in the Determination of Biomarkers, Drugs of Abuse and Medicines”, which will be published by the open access journal Molecules, is open for submissions should you have a relevant paper ready for publication. More details can be found here.

Date: 27 July 2021

Time: 3:00 pm CEST | 9:00 am EDT | 9:00 pm CST Asia

Webinar ID: 870 0489 2565

Webinar Secretariat: molecules.webinar@mdpi.com

Chair

National Institute of Legal Medicine and Forensic Sciences, Portugal

DETAILS
Bio
Mário Barroso is a specialist in forensic medicine and works at the National Institute of Legal Medicine and Forensic Sciences (Portugal). PharmD (University of Coimbra, 1999), Postgraduation in Forensic Toxicology (University of Coimbra, 2002), MsC (University of Coimbra, 2005), PhD in Toxicology (University of Beira Interior, 2010). Current interests: drugs and drug abuse; sample preparation; chromatographic analysis; analytical, clinical and forensic toxicology; hair analysis; accreditation and quality control issues; alternative specimens; establishment of cut-off values. He has published over 83 papers in scientific journals, including book chapters, 170 communications and 1 international patent.

Invited Speakers

Department of Chemistry, Aristotle University of Thessaloniki, Greece

DETAILS
Bio
Georgios Theodoridis is Professor of Analytical Chemistry at the Department of Chemistry, Aristotle University of Thessaloniki, Greece. He studied Chemistry (1990) and received his PhD (1994) in Separations Sciences from the Aristotle University. He then worked as a (post-doctorate) researcher at the Universities of Pardubice (CZ) and Leiden (NL), in AstraZeneca UK DMPK and as team leader at the Edmund Mach Foundation, Trento Italy. His research focuses on the application of LC-MS and GC-MS in metabolite profiling of nutritional metabolomics and foodomics. Emphasis is given on analytical method validation, QC and (bio)marker discovery. He leads the BIOMIC initiative of Aristotle University (http://biomic.web.auth.gr/) and the FoodOmicsGR_Research Infrastructure (http://foodomics.gr/). He has co-authored ca. 190 peer-reviewed articles, 20 book chapters and made more than 200 presentations in international meetings. He serves as Editor of J. Chromatography B, in the Editorial Board of Metabolites and in international think tanks and scientific bodies (EURACHEM, mQACC and other bodies).

Clinical and Forensic Toxicology Unit at Limoges University Hospital (France), Faculty of Pharmacy of Limoges

DETAILS
Bio
Franck Saint-Marcoux works equally between the University and the Hospital, where he is in charge of clinical toxicology, environmental toxicology and forensic science for both. - He is responsible for the Clinical and Forensic Toxicology Unit of the Limoges University Hospital (France). This unit deals with more than 2000 forensic cases per year. - He holds a position of Full Professor of Toxicology at the faculty of Pharmacy of Limoges. He received different scientific awards from international societies and is author or co-author of over 80 papers in peer-reviewed international journals. He is Past President of the TDM group of the French Society of Pharmacology and Therapeutics (SFPT) and is a Member of the Scientific Council of the Frenck Society of Analytical Toxicology (SFTA). He has been Scientific Councilor of the International Association of Therapeutic Drug Monitoring and Clinical Toxicology (IATDMCT) for 4 years (2013–2017).

University of Padova, University Hospital of Padova (Italy)

DETAILS
Bio
Donata Favretto is Professor of Forensic Toxicology at the University of Padova (Italy), Responsible for the Laboratory of Legal Medicine and Toxicology and Responsible for the Regional Antidoping Center at the University Hospital of Padova. She received her degree in Pharmaceutical Chemistry and Technology in 1990. She continued her academic enrichment specializing in Chemical Methodologies for Analysis and Control. From 1990 to 2001, she was a Researcher at the National Council of Researches at the Mass Spectrometry Center of Padova, where she focused her activity on the identification and characterization of organic molecules and biologically active compounds; she also had the opportunity to explore the potentials of the most advanced mass spectrometry techniques in the biomedical and clinical fields. In 2001, she moved to the Department of Legal Medicine—Forensic Toxicology and Antidoping, of Padova University Hospital, where she was actively involved in clinical and forensic toxicology. Since then, her research topics have been the diagnosis of acute and chronic intoxications, the determination of xenobiotics from biological fluids and complex matrices, the identification and quantification of drugs, drugs of abuse and metabolites, the dosage of neurodepressors, and the identification of doping agents. She continued her career, achieving the title of Associate Professor in Forensic Toxicology in 2006. She is pursuing her scientific and research activities at the Legal Medicine Institute of the University of Padova—Department of Public Health. She is responsible for the Laboratory of Legal Medicine and Toxicology and the Regional Antidoping Center. She is a Member of the Board of the International Association of Forensic Toxicologists (TIAFT). She is the President of the Italian Group of Forensic Toxicologists (GTFI). She has been a Member of the Board of the Society of Hair Testing since 2012, and the President since 2018.

Program

Speaker/Presentation

Time in CEST/CET

Dr. Mário Barroso

Chair Introduction

3:00 - 3:05 pm

Dr. Mário Barroso

Applications of Microextraction by Packed Sorbent in Forensic Toxicology

3:05 - 3:25 pm

Prof. Dr. Georgios Theodoridis

Validation and Quality Control for Metabolomics Analysis

3:25 - 3:45 pm

Prof. Dr. Franck Saint-Marcoux

Probe Electrospray Ionization Mass Spectrometry (PESI) for the Measurement of Illicit Drugs in Saliva

3:45 - 4:05 pm

Prof. Dr. Donata Favretto

Dried Blood Spots for the Monitoring of Drugs, Medicinal Drugs and Biomarkers in Blood

4:05 - 4:25 pm

Q&A Session

4:25 - 4:30 pm

Closing of Webinar

Dr. Mário Barroso

4:30 - 4:35 pm

Webinar Content

On Tuesday, 27 July 2021, MDPI and the Journal Molecules organized the 14th webinar on Molecules, entitled "Advances on Bioanalysis: Recent Approaches in the Determination of Biomarkers, Drugs of Abuse and Medicines".

The introduction was held by the Chair of the webinar, Dr. Mário Barroso. He is a specialist in forensic medicine and works at the National Institute of Legal Medicine and Forensic Sciences in Portugal. He got his master degree at the University of Coimbra, and a PhD in Toxicology at the University of Beira Interior. Among his current interest there are drug abuse; sample preparation; chromatographic analysis; analytical, clinical and forensic toxicology; and hair analysis. He has published over 83 papers in scientific journals, including book chapters.

The first speaker to quick off this webinar was Prof. Dr. Mário Barroso, with his presentation “Applications of Microextraction by Packed Sorbent in Forensic Toxicology”.

The second presentation with the title “Validation and Quality Control for Metabolomics Analysis” was held by Prof. Dr. Georgios Theodoridis. He is Professor of Analytical Chemistry at the Department of Chemistry, Aristotle University of Thessaloniki in Greece. He studied Chemistry and received his PhD in Separations Sciences from the Aristotle University. He then worked as a post-doctorate researcher at the Universities of Pardubice (CZ) and Leiden (NL), in AstraZeneca UK DMPK and as team leader at the Edmund Mach Foundation, Trento Italy. His research focuses on the application of LC-MS and GC-MS in metabolite profiling of nutritional metabolomics and foodomics.

The presentations were followed by a Q&A and a discussion, moderated by the Chair Dr. Mário Barroso. The webinar was offered via Zoom and required registration to attend. The full recording can be found here on Sciforum website. In order to stay updated on the next webinars on Molecules be sure to sign up for our newsletter by clicking on “Subscribe” at the top of the page.

Relevant SI

Advances on Bioanalysis: Recent Approaches in the Determination of Biomarkers, Drugs of Abuse and Medicines
Guest Editors: Dr. Mário Barroso, Prof. Dr. Eugenia Gallardo & Prof. Dr. Luís Passarinha
Deadline for manuscript submissions: 15 November 2021

Sponsors and Partners

Organizers

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