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Molecules Webinar | Multivalent Self-Assembled Systems for Biological Applications

Part of the MDPI Molecules Webinar series
31 Jan 2022, 14:00 (CET)

Self-assembly, Multivalency, Supramolecular Chemistry, Supramolecular Polymers, Dendrimers, Gene Delivery, Molecules
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Welcome from the Chair

30th Molecules Webinar

Multivalent Self-Assembled Systems for Biological Applications

Multivalency is a hallmark of biomolecular recognition, which applies to nucleic acids, proteins, and carbohydrates. The multivalent binding by synthetic nano-constructs is inspired by numerous biological systems such as viruses, and has strong potential in biological/biomedical applications, for instance, for the treatment of cancer or infectious diseases, as well as in targeted drug/gene/protein delivery and biosensing/bioimaging. Besides the rational or trial-and-error molecular engineering of multivalent systems, self-assembly approaches, using supramolecular or dynamic covalent chemistries, have emerged in the last two decades and attracted growing interest as a successful strategy for the identification of multivalent binders. Additionally, these multivalent self-assembled systems are dynamic and responsive, which enables the adaptation and the smart control of their self-assembly and disassembly by physico-chemical effectors. This webinar will showcase how self-assembly approaches can be implemented to provide the next generation of multivalent systems for biological applications.

Date: 31 January 2022

Time: 2:00pm CET | 8:00am EST | 9:00pm CST Asia

Webinar ID: 874 5499 6317

Webinar Secretariat:


Institut des Biomolécules Max Mousseron (IBMM), CNRS, Université de Montpellier, ENSCM, France

Sébastien Ulrich completed his PhD with Prof. Jean-Marie Lehn (Université de Strasbourg, France), and post-docs with Prof. Harry L. Anderson (Oxford University, UK) and Prof. Eric T. Kool (Stanford University, CA, USA). In 2011, he was awarded an ANR starting grant and joined the group of Prof. Pascal Dumy in Grenoble, before moving in 2012 to Montpellier, France, where he was recruited by the CNRS to develop his research interests in the field of supramolecular bioorganic chemistry. Since then, he has contributed to the development of dynamic self-assemblies for gene delivery applications. In 2017, he was awarded the CNRS Bronze Medal.

Invited Speakers

Department of Chemistry, Johannes Gutenberg University, Mainz, Germany - Website

Pol Besenius was born and raised in Luxemburg, and studied Chemistry in Vienna and Glasgow. He received his PhD from the University of Strathclyde in Glasgow (2008) und undertook postdoctoral studies at the Eindhoven University of Technology, as a Marie-Curie Fellow (2008–2011). He started his independent research group at the Organic Chemistry Institute in Münster, supported by a Liebig Fellowship in 2011, and moved to the Johannes-Gutenberg University of Mainz in 2015 to take up a Professorship in Macromolecular Chemistry. In 2018, he was awarded an ERC Consolidator Grant, and since 2018, he has acted as Editor for the newly launched Thieme journal Organic Materials.

Centre Interdisciplinaire de Nanoscience de Marseille, Aix-Marseille University, CNRS, UMR 7325 CINaM, France - Website

Dr. Ling Peng completed her PhD with Prof. Albert Eschenmoser at the Swiss Federal Institute of Technology in Zurich, Switzerland, and her postdoctoral research with Prof. Maurice Goeldner at University of Strasbourg in France. Dr. Ling Peng is currently a CNRS research director in France, and actively working at the interface of chemistry and biology. She has established bioinspired and self-assembling supramolecular dendrimers for drug delivery in cancer treatment and imaging. She was awarded with the Dr & Mme Henri Labbé Prize of the French Academy of Sciences, and became a Distinguished Member of the French Chemical Society.

Webinar Content

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Time in CET

Dr. Sébastien Ulrich

Chair Introduction

2:00 - 2:05 pm

Prof. Dr. Pol Besenius

Modular Vaccines Using Supramolecular Glycoconjugates

2:05 - 2:30 pm


2:30 - 2:40 pm

Dr. Ling Peng

Self-Assembling Supramolecular Dendrimers for Biomedical Applications

2:40 - 3:05 pm


3:05 - 3:15 pm

Closing of Webinar
Dr. Sébastien Ulrich

3:15 - 3:20 pm

Relevant SI

Multivalent Self-Assembled Systems for Biological Applications
Guest Editor: Dr. Sébastien Ulrich
Deadline for manuscript submissions: 28 February 2022

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