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Pathogens Webinar | Latest Updates on Gastroenteric Viruses

28 September 2021
15:30 (CEST)
Online

Welcome from
the chair

4th Pathogens Webinar

Latest Updates on Gastroenteric Viruses

Acute gastroenteritis (AGE) is one of the most common illnesses in humans worldwide, being responsible for half a million deaths among children aged < 5 years, mostly in developing countries. Although in industrialized nations deaths from AGE are rarely seen, gastrointestinal diseases remain an important cause of morbidity in younger children resulting in substantial medical and healthcare expenses, lost productivity, and other costs to society and families. Enteric viruses have been recognized as the most significant etiologic agents of AGE in children and four viruses are being considered as clinically relevant: group A rotavirus (RVA), norovirus (NoV), adeno virus 40/41 (AdV) and astrovirus (AstV). These viruses are characterized by a high genetic and antigenic variability, due to evolutionary mechanisms such as rearrangement, re-assortment, inter-species transmission and positive accumulation of point mutations. The continuous emergence and re-emergence of several variants poses challenge for their classification, but also for development of diagnostics assays and suitable vaccines. The aim of this webinar is to focus on the temporal pattern of evolution of the main enteric viruses. In particular, large-scale surveillance studies on RVA, NoV and AstV will be showed in order to update information about their genetic evolution over the time. Moreover, the experience acquired on RVA vaccine will be presented to underline the importance of molecular epidemiology investigation as a valuable baseline information for new vaccines development.

Date: 28 September 2021

Time: 3:30pm CEST | 9:30am EDT | 9:30pm CST Asia

Webinar ID: 881 3272 0184

Webinar Secretariat: pathogens.webinar@mdpi.com



Meet Our Speakers

Prof. Dr. Simona De Grazia

Prof. Dr. Simona De Grazia

Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties;
Simona De Grazia is an Associate Professor of Microbiology and Clinical Microbiology at the Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, Italy. She obtained her Specialization in Clinical Microbiology and Virology in 2004 and from 2005 to 2014 was Researcher at the Medicine Faculty, Department of Health Promotion Sciences, University of Palermo. Her research is devoted to study genetic evolution and molecular epidemiology of human enteric viruses such as rotavirus, norovirus and astrovirus. Prof De Grazia is author/co-author of 78 publications in international journals (h-index: 26; total citations: 1768) and peer-reviewer for numerous international publication. She has teaching experience of graduate Microbiology courses at the Medical, Rehabilitation therapy, Nursing, Biotechnology Schools and of postgraduate Microbiology courses at the Microbiology and Virology and Infectious and Tropical Diseases Specialization Schools, of Infectious-Master course in Laboratory Medicine and PhD course in Experimental Oncology and surgery at the University of Palermo and of the PhD course in Animal Health and Zoonotic Infections at the University of Bari. She is member of national scientific societies including: the “Società Italiana di Microbiologia” (SIM) and the “Società Italiana di Virologia Medica” (SIVM).

Sponsors and Partners

Organizer


MDPIPathogens
Webinar Content
On Tuesday, 28 September 2021, MDPI and the Journal Pathogens organized the 4th webinar on Pathogens, entitled " Latest Updates on Gastroenteric Viruses".

The introduction was held by the Chair of the webinar, Prof. Dr. Simona De Grazia, from the Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo in Italy. She opened the session with a short presentation of the principal mechanisms of virus evolution, and put the basis for a successful discussion on Gastroenteric Viruses.

The first presentation made by Dr. Max Ciarlet, focused on the efficacy of Rotavirus vaccines with a particular attention to developing countries were the rate of mortality for rotavirus infection is still high. Dr. Paolo Capozza, highlighted in second talk, the milestones of rotavirus discovery and the role of animals as source of novel human viruses. Continuing this trail of explanation, Dr. Floriana Bonura, showed the Norovirus GII.4 genetic evolution, with over more than 30 years of epidemiological surveillance. Finally, common and novel Astroviruses and their pathogenetic interaction with the host were presented by Dr. Susana Guix.

The presentations were followed by a Q&A and a discussion, moderated by the Chair Professor De Grazia. The webinar was offered via Zoom and required registration to attend. The full recording can be found here on Sciforum website. In order to stay updated on the next webinars on Pathogens be sure to sign up for our newsletter by clicking on “Subscribe” at the top of the page.


Relevant SI
Pediatric Gastroenteritis and Related Viral Infections

Guest Editors: Prof. Dr. Simona De Grazia, Dr. Floriana Bonura
Deadline for manuscript submissions: 1 October 2021


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