
Viral hepatitis is a substantial part of non-alcoholic liver diseases. Hepatotropic viruses may serve as cytotoxic and non-cytotoxic agents driving the disease progression, which potentially may lead to chronic liver injury. Co-infections with other hepatotropic viruses increase the pathogenesis of viral hepatitis and the progression to end-stage liver diseases. Non-alcoholic steatohepatitis is one of the common features accompanying viral hepatitis development but the mechanisms behind this are not quite clear. In this Webinar, we will focus on some aspects of liver-associated HIV-infection as well as on potentiation of HIV with HCV-infection. In addition, since chronic hepatitis B (CHB) is still considered as an uncurable infection, we will overview new therapeutic targets for CHB treatment and the application of long-acting nucleoside reverse transcriptase inhibitors as a potential medication for this infection.
Date: 14 December 2021
Time: 3:00pm CET | 9:00am EST | 10:00pm CST Asia
Webinar ID: 890 0786 5051
Webinar Secretariat: biology.webinar@mdpi.com


On Tuesday, 14 December 2021, MDPI and the Journal Biology organized the 2nd Webinar on Biology, entitled "Infection-Associated Liver Diseases" and chaired by Prof. Dr. Natalia Osna from the Department of Internal Medicine, University of Nebraska Medical Center, USA. This online seminar was devoted to currently incurable viral infections, which finally lead to end-stage liver diseases. These viruses are HIV (potentiated or not by HCV) and HBV.
The crucial pathogenic and treatment aspects of these infections were covered by presentations at the Webinar. First two talks, given by Prof. Dr. Kenneth E. Sherman and Prof. Dr. Richard K. Sterling, were based on the clinically relevant role and mechanisms of steatosis development in HIV-infection and HCV-HIV co-infection. Second two talks, given by Dr. Sandra Phillips and Prof. Dr. Larisa Poluektova, concentrated on chronic hepatitis B treatment and overviewed pathomechanisms of HBV-infection, osteopontin as a treatment target for HBV, and recently developed long-acting nucleoside reverse transcriptase inhibitors as a promising therapeutics. All speaker presentaitons were followed by Q&A sessions moderated by the chair.
The webinar was offered via Zoom and required registration to attend. The full recording can be found below. In order to stay updated on the next webinars on Biology, be sure to sign up for our newsletter by clicking on “Subscribe” at the top of the page.