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Cells, Cells and Nothing but Cells: Discoveries, Challenges and Directions

6–8 Mar 2023

Stem Cells, Organelle Function, Cellular Metabolism, Cellular Pathology, Cardiovascular System, Motility and Adhesion, Cellular Immunology, Aging
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Dear Colleagues,
Cells 2023 has officially come to an end! We would like to thank our conference chair, session chairs, speakers, and all the attendees for making this a great meeting.
You can download an electronic Certificate of Attendance by accessing your dashboard on Sciforum.net. Please login with the same email you used to register to the conference. The certificate will be found under "My Certificates".

Welcome from the Chair

On behalf of Cells I welcome you to our 2023 grand virtual Conference. The objective of this event is to bring together all researchers and scholars to discuss a wide range of topics covering the aim and scope of Cells. We envision this Conference as a highly interactive forum which is open to diverse forms of interaction between its participants. Currently, Cells serves as a platform covering a broad range of topics including cell signaling, stem cells, organelle function, reproduction and aging, autophagy and metabolism, and other aspects of cell physiology. Cells is the journal of choice for researchers who need a quick turnaround time in reviewing and publishing their papers. We can be proud of the fact that we have a high number of repeat contributing authors, which sends a strong message to research community that Cells is recognized as a high quality service provider with an impeccable reputation because of its peer review and revision process.

We expect that participants of this Conference can exchange novel provocative ideas by presenting short oral presentations on research and development discoveries, as well as emphasize challenges facing Cell Biology as a discipline and the priority of critical health issues, we should focus on using cell biology tools and techniques.

Download the conference flyer and share it with your colleagues!

Conference Chair,

Dr. Alexander E. Kalyuzhny

Sponsored by:


Conference Secretariat
Ms. Sara Ottolini
Ms. Laura Wei
Ms. Rainy Han

Email: cells2023@mdpi.com

Follow us on Social Media

#Cells2023

Conference Chair

Neuroscience, UMN Twin Cities, Minneapolis, USA

DETAILS
Bio
Opioid analgesics are currently the first choice drugs for the treatment of pain. Although opioid analgesics have been found to produce antinociception through interaction with pharmacologically distinct G protein-coupled mu-, delta- and kappa-opioid receptors, the mechanism underlying the function of these receptors is not fully understood. For example, a fundamental question remains regarding the functional relevance of heteromeric mu/delta and mu/kappa-opioid receptors. My research interests are focused on investigating the mechanisms underlying constitutive and induced heteromerization of opioid receptors using double-transfected HEK-293 cells as a model, as well as primary sensory neurons isolated from the dorsal root ganglia and cultured in vitro. The study is aimed at determining how opioid receptors form mu/delta- and mu/kappa heteromers as well as at investigating heteromerization of opioid receptors with non-opioid ones, including chemokine CCR5 and CXCR4, and glutamate mGluR5 receptors. In addition, studies are done to reveal the effects of ligands with dual agonist/antagonist activity on receptor trafficking and heteromerization using advanced multi-color fluorescence immunocytochemistry, confocal microscopy, and image analysis techniques. These studies will shed light on the function of opioid receptors and will also help to clarify the role of chemokine and glutamate receptors in modulating the antinociceptive activity of opioid analgesics.

Session Chairs

Prof. Dr. Ritva Tikkanen

Institute of Biochemistry, Medical Faculty, Justus-Liebig University of Giessen, Germany

DETAILS
Biography
Vice Chair of the Institute of Biochemistry Medical Faculty, University of Giessen, Germany. Research areas: Development of personalized therapies for rare diseases (lysosomal storage disorders and SSADH deficiency); Autoimmune diseases (Pemphigus vulgaris); Vesicular membrane trafficking, lysosomal biogenesis & lysosomal storage diseases; Cell adhesion and cell polarity.

Dr. Alexander V. Ljubimov

Biomedical Sciences and Neurosurgery, Regenerative Medicine Institute Eye Program, Cedars-Sinai Medical Center, Medicine, UCLA School of Medicine, Los Angeles, CA, USA

DETAILS
Biography
Dr. Alexander Ljubimov is an internationally recognized eye and cancer researcher, with over 130 peer-reviewed papers, reviews, and book chapters published. He is Director of Regenerative Institute Eye Program at Cedars-Sinai Medical Center, and Professor of Biomedical Sciences and Neurosurgery. Dr. Ljubimov is also Adjunct Professor of Medicine at the David Geffen School of Medicine at UCLA. His research interests include using innovative gene and nano therapy to restore normal stem cell functions in diabetic corneas, and studying new inhibitors of a key cellular enzyme CK2 that block abnormal retinal vessel growth in diabetic retinopathy. He is also developing new targeted nanotherapeutics for cancer and eye diseases, and directs studies aiming at making corneal cells from induced pluripotent stem cells. Dr. Ljubimov's research has been funded by NIH since 1995 (PI on three current R01 grants). He has been serving on numerous NIH Study Sections, and has been a grant reviewer for various agencies in U.S., U.K., France, Italy, Switzerland, Belgium, Australia, and the Netherlands. Dr. Ljubimov is an Editorial Board member of 15 scientific journals including Investigative Ophthalmology and Visual Science, Progress in Retinal and Eye Research, Experimental Eye Research, Molecular Vision, Experimental Biology and Medicine, PLoS One, Scientific Reports, and Ocular Surface. He is Gold Fellow of the Association for Research in Vision and Ophthalmology (ARVO) and Overseas Fellow of the Royal Society of Medicine (U.K.). Dr. Ljubimov received his summa cum laude M.S. degree from Moscow State University (Moscow, Russia), and his Ph.D. and D.Sc. degrees from the Russian Cancer Research Center. He completed postdoctoral training in the International Agency for Research on Cancer in Lyon, France. He has a background in cancer research and is working on corneal and retinal diseases since 1993.

Prof. Dr. Paolo Bernardi

Department of Biomedical Sciences, University of Padova, Italy

DETAILS
Biography
Paolo Bernardi is a Professor and former Chair, Department of Biomedical Sciences of the University of Padova. He also served as deputy Dean, Medical Faculty. His studies on the role of mitochondria in disease pathogenesis contributed substantially to developing this field. His recent molecular definition of the permeability transition pore holds great promise for the treatment of degenerative diseases like muscular dystrophies through the development of mitochondrial drugs. Paolo Bernardi earned his M.D. at the University of Padova (Italy) and completed his education in Cellular and Molecular Biology as an NIH-Fogarty fellowship at the Whitehead Institute for Biomedical Research – M.I.T.

Dr. Christian Neri

Institute of Biology Paris-Seine, Sorbonne Université and CNRS, Paris, France

DETAILS
Biography
Christian Neri, Research Director at INSERM and Associate Professor at the University of Montreal, joined INSERM in 2002 after 8 years spent at the Human Polymorphism Study Center in Paris following postdoctoral studies in the USA and UK. Dr. Neri oversees national and international research programs on cellular resilience-over-senescence in neurodegenerative diseases (Huntington’s disease, Alzheimer’s disease), multidisciplinary approaches and precision medicine. Dr Neri has published +100 papers in genome sciences, machine learning, C. elegans genetics, cell biology and preclinical/clinical research. Dr. Neri holds a Ph.D./HDR in Health Sciences from Sorbonne Université in Paris and a Ph.D. in Cell Biology and Microbiology from the University of Aix-Marseille, France.

Prof. Dr. Christoph Englert

Leibniz Institute on Aging - Fritz Lipmann Institute, Jena, Germany

DETAILS
Biography
Christoph Englert studied Biochemistry in Tübingen and Munich. Having received his PhD from the Max Planck Institute for Biochemistry / University of Munich in 1992, he carried out his postdoctoral training with Daniel Haber at the Cancer Center of Massachusetts General Hospital / Harvard Medical School. Returning to Germany, Christoph became a junior group leader in Karlsruhe in 1996 and in 2002 became an Associate Professor of Physiological Chemistry at the University of Würzburg. Since 2004 he has been a Full Professor at the University of Jena and is also a senior group leader at the Leibniz Institute on Aging – Fritz Lipmann Institute (FLI). Research in the Englert lab focuses on the relationship between the development of an organism and disease. Expanding this topic, he, together with a colleague, has established and developed a short-lived African killifish, Nothobranchius furzeri, as a new model for age research. This provided the opportunity to combine his experience and interest in questions of developmental genetics with relevant questions of age research. Currently, a number of projects in his lab utilize N. furzeri, allowing the investigation of the age-dependency of organ homeostasis and regeneration as well as the genetic basis of aging. In 2015 the work on Nothobranchius at FLI has culminated in the high-ranking publication of its genome, which provided a number of novel insights into the biology of aging.

Prof. Dr. Kay-Dietrich Wagner

Université Côte d’Azur, CNRS, INSERM, iBV, Nice, France

DETAILS
Biography
Interests: vessel formation in development and disease; transcriptional control; epigenetics; cancer; cardiovascular disease

Prof. Dr. Francisco Rivero

Hull York Medical School, University of Hull, UK

DETAILS
Biography
Dr Rivero is a molecular cell biologist who specialises in research into functional and regulatory aspects of the cytoskeleton and its relevance in disease processes. Dr. Rivero obtained his MD from the University of Valladolid and his PhD at the Institute of Biochemistry, CSIC-Universidad Complutense, Madrid. After postdoctoral research fellow roles at the Max-Planck Institute for Biochemistry, Martinsried and at the University of Cologne in Germany he was appointed Scientific assistant and Group leader at the Center for Biochemistry, Medical Faculty, University of Cologne. In 2007 he joined the Hull York Medical School as a Senior Lecturer and was promoted to Reader in 2017.

Prof. Dr. Alessandro Poggi

Ospedale Policlinico San Martino, Italy

DETAILS
Biography
Alessandro Poggi MSc, MD has been working on cellular and tumor immunology for more than 35 years. He is author of 248 original articles published on indexed journals and he serves as a reviewer and/or editor of several scientific journals. He is director of the Molecular Oncology and Angiogenesis Unit at the IRCCS Ospedale Policlinico San Martino in Genoa. At present, his main research interests are the tumor microenvironment (TME) and regulation of anti-tumor immune response. Further, he is studying the delivery of immune activating drugs to tumor in three-dimensional culture systems such as tumor organoids and spheroids. (Scopus ID 7101947825 https://www.scopus.com/authid/detail.uri?authorId=7101947825; Laboratory website: https://www.ospedalesanmartino.it/ospedale/dipartimenti/in-line-direttore-scientifico/item/388-oncologia-molecolare-e-angiogenesi.html).

Invited Speakers

Dept. of Biology and VIMM, University of Padova, Italy

DETAILS
Bio
Luca Scorrano is Professor of Biochemistry at the Department of Biology, University of Padua (Italy). He completed his Medical Degree (1996) and his PhD in Molecular and Cellular Biology and Pathology (2000) at the University of Padua with Paolo Bernardi. From 2000 to 2003 he was Human Frontier Science Program (HFSP) postdoctoral fellow at Dana-Farber Cancer Institute, Harvard Medical School in Boston (USA), in the lab of the late Stanley J. Korsmeyer, a founding father of the field of apoptosis. In 2003 he was awarded an Assistant Scientist position at the Dulbecco-Telethon Institute, in 2006 he was recruited as Full Professor at the Dept. of Cell Physiology and Metabolism of the University of Geneva Medical School (Switzerland). In 2013 he moved to the University of Padova as Professor of Biochemistry and from 2014 to 2020 he served as Scientific Director of the Veneto Institute of Molecular Medicine. The work of L. Scorrano addresses the central question of form-function relationship at the molecular level. During his career, he has changed classical tenets in the fields of apoptosis, mitochondrial pathophysiology, and medicine. His work on cristae remodeling paved the way for the new field of mitochondrial dynamics.

Senior lecturer, Department of Anatomy and Physiology, The University of Melbourne,
Adjunct Senior Research Fellow, Australian Regenerative Medicine Institute, Monash University

DETAILS
Bio
Dr Ruparelia is a senior lecturer and group leader in the Department of Anatomy and Physiology at The University of Melbourne. Her group is investigating the biology of skeletal muscle ageing, examining processes such as muscle fiber atrophy and growth, muscle stem cell dynamics, muscle regeneration, and metabolism. For her research program, she not only uses the unique advantages of the zebrafish model, but she also uses a new experimental system – that of the African killifish, whose extremely short lifespan makes it an attractive model for ageing research.

Leibniz Institute on Aging – Fritz-Lipmann Institute (FLI), Jena, Germany

DETAILS
Bio
K. Lenhard Rudolph is senior group leader at the Leibniz Institute on Aging – Fritz-Lipmann Institute (FLI) in Jena. From 2012-2017 he was the scientific director of the FLI. He received several prestigious research grants and awards including Emmy-Noether-funding, a Heisenberg-Professorship, the Gottfried-Wilhelm Leibniz award of the German Research Foundation (DFG), and an advanced grant of the European Research Council (ERC). His main contributions include the first description of the role of telomere dysfunction in stem cell and organism aging. His work showed that alterations in epigenetic stress responses of aging stem cells lead to aberrant activation of developmental pathways and stem cell dysfunction. His current work identifies aging-associated metabolic alterations that limit the function of stem cells and organ maintenance. Based on this knowledge his group aims to develop new interventions that can be used in late life to improve health at old age.

Institute of Anatomy, LMU in Munich, Germany

DETAILS
Bio
Anna Sigmund is a group leader at the Institute of Anatomy at the LMU in Munich. She studied biology with focus on cell biology at the LMU in Munich and did her PhD investigating TLR-signalling at the Institute of Medical Microbiology and Immunology in Essen. Now her research focuses on cell contacts and desmosomal adhesion in the skin. Here she investigates desmosomal interaction- and signalling mechanisms especially in the context of the autoimmune blistering disease pemphigus to establish new treatment paradigms directly targeting keratinocyte adhesion.

Professor of Cell Biology, Shmunis School of Biomedicine and Cancer Research, and Sagol School of Neuroscience, Tel Aviv University, Israel.

DETAILS
Bio
Ph.D. at Leloir Institute, University of Buenos Aires, Argentina, 1986 Postdoctoral fellow at Whitehead Institute, Cambridge, MA, USA Faculty position at Tel Aviv University since 1991 Visiting professor at Harvard Medical School and Boston Children’s hospital Research overview: Mechanisms of endoplasmic reticulum (ER) quality control and delivery of misfolded proteins to ER-associated degradation (ERAD). How these processes are regulated by cellular stress and how this relates to diseases where ER stress and protein misfolding is central, especially neurodegenerative diseases, focusing on models of Huntington’s disease.

Center for Integrative Genomics (CIG), University of Lausanne, Switzerland,
Lee Kong Chian School of Medicine, Nanyang Technological University Singapore & Imperial College London, Singapore

DETAILS
Bio
Walter Wahli received his PhD from the University of Bern in Switzerland. He was a postdoc at the Carnegie Institution of Washington in Baltimore, and a Visiting associate at the National Cancer Institute, NIH, Bethesda USA. He then became Professor and Director of the Institute of Animal Biology of the University of Lausanne (UNIL), Switzerland, where he also was Vice-rector. He founded the Center for Integrative Genomic (CIG), which he directed until 2005. He was a member of the Swiss National Science Foundation research council and presided over the Biology and Medicine Division. He is an elected member of the EMBO and of several academies. He received the Otto-Naegeli Prize (2002), the European Federation of Lipid Research Award (2002), the Hartmann Müller Prize (2008) and the Lifetime Achievement Award from the UNIL Faculty of Biology and Medicine (2011). He is currently a Professor emeritus at UNIL and Visiting Professor of Metabolic Disease in Lee Kong Chian School of Medicine, Nanyang Technological University Singapore. The contributions of Walter Wahli over the last 40 years unfold logically in a series of discoveries that contributed in advancing our understanding of the molecular mode of action steroid hormones, fatty acids and derivatives, which signalling impacts most key biological processes in vertebrates. Notably, he has worked and still works on the nuclear receptors Peroxisome Proliferator Activated Receptors, known as PPARs, involved in energy metabolism and explores the potential of PPARs as drug targets in metabolic diseases.

University of Modena and Reggio Emilia,
Centre for Regenerative Medicine "Stefano Ferrari"

DETAILS
Bio
Graziella Pellegrini is Full Professor at the University of Modena and Reggio Emilia and Cell Therapy Program Coordinator at the Centre for Regenerative Medicine "Stefano Ferrari". She is also co-founder of Holostem Terapie Avanzate S.r.l. She has a Master Degree in Chemistry and Pharmaceutical Technologies and a Master Degree in Pharmacy at the University of Genova. She was one of the two inventors of the technology for culture and transplantation of limbal stem cells for the treatment of blindness due to corneal stem cell deficiency; she discussed and obtained the orphan drug designation and European registration of this corneal stem cell therapy. She developed several translational medicine protocols for treatment of third-degree burns, depigmentation disorders and a successful phase I clinical trial on gene therapy of epidermolysis bullosa. She is currently working with her team, on oral mucosa and urethra for a phase I clinical trial and translational research on airway epithelium. Author of many patents, book chapters and international peer reviewed publications in the major international peer-review journals, as New England Journal of Medicine, Nature, Lancet and was invited speaker or chairman in over 250 major scientific meetings all over the world. Prof. Pellegrini is founding member of the International Ocular Surface Society and member of many major scientific societies and international committees.

German Center for Neurodegenerative Diseases (DZNE), Germany

DETAILS
Bio
Alexander Dityatev is the head of the Molecular Neuroplasticity research group at DZNE and a full professor at the University of Magdeburg. His group is studying the role of extracellular matrix (ECM) molecules in major brain diseases and developing new strategies to image and target the ECM. Working together with Melitta Schachner at the Center for Molecular Neurobiology Hamburg, Dr. Dityatev uncovered synaptic functions of several cell adhesion and extracellular matrix molecules, such as tenascins, chondroitin sulfate proteoglycans, NCAM, L1, CHL1, and their associated glycans. Being a Senior Researcher at the Italian Institute of Technology, Dr. Dityatev published several mechanistic studies uncovering how synaptic plasticity and learning are regulated by polysialylated form of NCAM and hyaluronic acid through regulation of extrasynaptic GluN2B receptors and L-type Ca2+ channels. Dityatev's research group in Magdeburg recently reported on several treatments - targeting extracellular proteolysis, synaptogenesis and ECM remodelling - to suppress epileptogenesis and rescue cognitive functions in mouse models of dementia. Dr. Dityatev graduated in Mathematics at the Leningrad State University and accomplished his Ph.D. in Biology at the Sechenov Institute of Evolutionary Physiology and Biochemistry in Leningrad.

Head of Department of Biotechnology and Biosciences, Full Professor of General Pathology, University of Milano-Bicocca, Italy

DETAILS
Bio
Francesca Granucci received her PhD in Pharmacology and Toxicology from the University of Milan in 1996. She then performed the Post doc at the Dana Farber Cancer Institute – Boston. From 1998 to 2001 she worked as Research Associate at the CNR in Milan and from 2001 to 2006 she worked as Research Associate at the University of Milano-Bicocca. She is currently Full Professor of General Pathology at the Department of Biotechnology and Biosciences of the University of Milano-Bicocca. In 2012 she obtained the EFIS-EJI Ita Askonas prize as best female group leader in immunology and in 2019 the IUBMB Jubilee Lecturer medal for her outstanding contributions to understanding the mechanisms of innate immunity. Prof. Granucci has pioneered systems biology approaches to study host-pathogen interactions. She has described specific molecular events occurring during the interaction of dendritic cell with gram-negative bacteria and in inflammation.

Wellcome Trust Centre for Cell-Matrix Research; University of Manchester

DETAILS
Bio
Pat is based within the Wellcome Trust Centre for Cell Matrix Research at the University of Manchester. Pat studied Biochemistry at the University of Nottingham, before undertaking a PhD at the University of Leicester and a postdoc in Jim Norman’s lab at the CRUK Beatson Institute. Pat established his lab in 2010, focussing on how cell-matrix interactions through integrins generate signals that control key cellular processes such as cell migration, differentiation and survival. The lab is specifically interested in how dynamic membrane processes control cell matrix interactions and the cytoskeleton, in particular how vesicular trafficking and membrane mechanics regulate matrix assembly and cell migration in 3D matrix.

CEO of CELLphenomics and ASC Oncology

DETAILS
Bio
Dr. Christian Regenbrecht mainly focusses on system oriented tumor research using three dimensional organoid tumor models. After studying biology and philosophy at the Rheinische Friedrich-Wilhelms-Universität in Bonn, he was awarded his doctorate in natural sciences under the supervision of Otmar Wiestler at the University Hospital in Bonn in 2005. He then worked at the Max Planck Institute for Molecular Genetics in Berlin as a research assistant to Hans Lehrach. Together with his research group, he moved to the Charité in Berlin in 2010, where he not only headed the “Tumor Stem Cells” research group at the Institute of Pathology until 2016, but also the central laboratory for functional genome research from 2012 to 2014. Having also been involved in excellent peer-reviewed international research projects since 2010, he founded the company CELLphenomics GmbH in June 2014. The 3D cell culture models (PD3D® models) developed there from tumor samples are used in research to further develop cancer drugs. The generated tumor models map the original tumor with unprecedented reliability. Outside the human body, these precise copies of the tumor in the patient allow to make an accurate and differentiated prediction on the likelihood of the cancer drugs’ efficacy (and inefficacy). Since founding ASC Oncology GmbH in March 2019, Dr. Regenbrecht has made the Reverse Clinical Engineering® test procedure that he developed directly available to patients, oncologists, and clinics. He is currently habilitating at the Universitätsmedizin Göttingen.

Tumor Biomechanics lab, INSERM UMR_S1109, Strasbourg, France

DETAILS
Bio
Vincent is a researcher in the Tumor Biomechanics lab, in Strasbourg (INSERM U1109). His work focuses on the cell-cell communication mediated by extracellular vesicles (EVs) during tumor progression and metastasis. With his group, he investigates the molecular mechanisms driving EV secretion, how tumor EVs spread in the organism via the circulation to reach distant organs and how they alter the local microenvironment to induce the formation of pre-metastatic niches. To do this, they combine photonic and electronic microscopy and use a combination of in vitro (microfluidics) and in vivo (zebrafish, mouse) models adapted to EVs tracking.

Eivor and Alston Callahan Endowed Chair, Department of Ophthalmology and Visual Science, University of Alabama at Birmingham, Alabama

DETAILS
Bio
Dr. Maria Grant, M.D., FARVO, is the Eivor and Alston Callahan Endowed Chair and Professor of Department of Ophthalmology and Visual Science. Dr. Grant completed her Medical Degree and Internship, residency and fellowship in Endocrinology and Metabolism at the University of Florida. She completed a Research Fellowship in the Department of Ophthalmology at Johns Hopkins University. Dr. Grant’s laboratory is interested in understanding the role of bone marrow cells and vascular wall cells in vascular repair in diseases such as in aging and diabetes. Dr. Grant’s research focus on understanding the biology of hematopoietic and endothelial stem and progenitor cell emergence, maintenance, and their regenerative properties. More recently she has examined the role of the renin angiotensin system in the intestine and how that impacts glucose homeostasis and immune function in aging and diabetes. She has served as principle/co-investigator on more than thirty five extramural foundation/NIH grants that have led to more than 260 peer reviewed publications.

Recordings

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Until 8th February 2023
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Until 27th February 2023
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Program Overview

The preliminary program of Cells 2023: Cells, Cells and Nothing but Cells: Discoveries, Challenges and Directions is now available.

Program Structure
Monday 6 March 2023
Tuesday 7 March 2023
Wednesday 8 March 2023

Welcome from the Chair

Session 1. Stem Cells

Chaired by Prof. Dr. Alexander V. Ljubimov

Session 3. Cellular Metabolism

Chaired by Dr. Christian Neri

Session 6. Cells of the Cardiovascular System

Chaired by Prof. Dr. Kay-Dietrich Wagner

Lunch Break
Lunch Break Coffee Break
Session 2. Organelle Function

Chaired by Prof. Dr. Paolo Bernardi

Session 4. Molecular and Cellular Mechanisms of Aging and Regeneration

Chaired by Prof. Dr. Christoph Englert

Session 7. Cell Motility and Adhesion

Chaired by Prof. Dr. Francisco Rivero

Coffee Break Lunch Break
Poster Session
Session 5. Cellular Pathology

Chaired by Prof. Dr. Ritva Tikkanen

Closing Session & Awards Ceremony

Detailed Program

Monday, 6th March 2023

Session
Time in CET
Speaker
10:00 - 10:05 Welcome from the Chair & Introduction
Session 1. Stem Cells

Session Chair: Prof. Dr. Alexander V. Ljubimov
10:05 - 10:30

Invited Speaker Dr. Maria B. Grant

Mesoderm subset derived from human pluripotent stem cells from diabetic and nondiabetics improve retinal pathology in a model of type 2 diabetes.

10:30 - 10:35 Q&A
10:35 - 10:45

sciforum-067354: Fabrizio Fontana

High mitochondrial mass identifies a subpopulation of vemurafenib-resistant cancer stem cells in melanoma

10:45 - 10:50 Q&A
Break Time 10:50- 11:15
11:15 - 11:40

Invited Speaker Prof. Dr. Graziella Pellegrini & Dr. Eleonora Maurizi

Development of therapies for the two sides of the cornea

11:40 - 11:45 Q&A
11:45 - 11:55

sciforum-067489: David Hay

Building Implantable Human Liver Tissue from Pluripotent Stem Cells

11:55 - 12:05

sciforum-068522: Francesca Natale

Progenitor High Fat Diet multigenerationally impairs Hippocampal Neural Stem Cell Niche

12:05 - 12:10 Q&A
Lunch break 12:10 - 14:00
Session 2. Organelle Function

Session Chair: Prof. Dr. Paolo Bernardi
14:00 - 14:25

Invited Speaker Prof. Dr. Gerardo Lederkremer

Compartmentalization and trafficking in endoplasmic reticulum protein quality control

14:25 - 14:30 Q&A
14:30 - 14:40

sciforum-067350: Luigi Donato

Impaired nuclear and mitochondrial cross-talk might alter mtDNA epigenetic regulation in maternally inherited diabetes and deafness affected patients

14:40 - 14:50

sciforum-067374: Daniel Gómez

Pioneering organelle structural biology: Golgi apparatus dysfunction and cascades of fatal pathways in cancer

14:50 - 15:00

sciforum-068934: Irène Tatischeff

Huge Modification of the Cell Theory by the Recent Discovery of the Widespread Cell-derived Extracellular Vesicles

15:00 - 15:10 Q&A
Break Time 15:10 - 15:25
15:25 - 15:50

Invited Speaker Prof. Dr. Luca Scorrano

Keeping mitochondria in shape: a matter of cell life and death

15:50 - 15:55 Q&A
End of day 1 - closing
Poster Session
Zoom Break-Out Rooms 16:00 - 17:00

Tuesday, 7th March 2023

Session
Time in CET
Speaker
Session 3. Cellular Metabolism

Session Chair: Dr. Christian Neri
11:00 - 11:25

Invited Speaker Dr. Vincent Hyenne

Blood flow diverts extracellular vesicles from endothelial degradative compartments to promote angiogenesis

11:25 - 11:30 Q&A
11:30 - 11:40

sciforum-064284: Ilana Kolodkin-Gal

Molecular genetics for probiotic engineering: How fermentatable sugars affect aggregation, adhesion and agression in Lactobacillaceae

11:40 - 11:50

sciforum-067012: Kai Christian Sonntag

Identification of an Inherent Bioenergetic and Metabolic Phenotype in Late-Onset Alzheimer Disease

11:50 - 12:00

sciforum-068134: Caterina Morabito

Microgravity-induced metabolic response in 2D and 3D TCam-2 cell cultures

12:00 - 12:10 Q&A
Lunch break 12:10 - 14:00
Session 4. Molecular and Cellular Mechanisms of Aging and Regeneration

Session Chair: Prof. Dr. Christoph Englert
14:00 - 14:25 Invited Speaker Prof. Dr. Lenhard Rudolph
14:25 - 14:30 Q&A
14:30 - 14:40

sciforum-064438: Volker Enzmann

Characterization of glial response during retinal degeneration / regeneration in experimental laser models

14:40 - 14:45 Q&A
14:45 - 15:10

Invited Speaker Dr. Avnika Ruparelia

Does skeletal muscle stop ageing physiologically?

15:10 - 15:15 Q&A
Break Time 15:15 - 15:30
Session 5. Cellular Pathology

Session Chair: Prof. Dr. Ritva Tikkanen
15:30 - 15:40

sciforum-065301: Marzia Di Donato

New approaches targeting the invasive phenotype of prostate cancer-associated fibroblasts

15:40 - 15:50

sciforum-067399: Malka Cohen-Armon

An Unveiled Cell-Death Mechanism Exclusive to Human Cancer Cells

15:50 - 16:00

sciforum-067861: Kamila Sobczak

The effect of synergistically combination of vitamin D and doxorubicin on the MCF-7 line breast cancer cells.

16:00 - 16:10

sciforum-069865: Miroslava Didiasova

Towards enzyme replacement therapy as a treatment for SSADH-deficiency

16:10 - 16:25 Q&A
16:25 - 16:50

Invited Speaker Dr. Christian Regenbrecht

Implication of intra-tumor heterogeneity on colorectal cancer response to MEK inhibition

16:50 - 16:55 Q&A
16:55 - 17:20

Invited Speaker Dr. Anna Sigmund

Apremilast is protective in pemphigus by a Plakoglobin-dependent stabilization of keratinocyte adhesion

17:20 - 17:25 Q&A
End of day 2 - closing

Wednesday, 8th March 2023

Session
Time in CET
Speaker
Session 6. Cells of the Cardiovascular System

Session Chair: Prof. Dr. Kay-Dietrich Wagner
10:00 - 10:25

Invited Speaker Prof. Dr. Walter Wahli

Roles of PPARα in Liver Health and Diseases

10:25 - 10:30 Q&A
10:30 - 10:40

sciforum-067369: Concetta Scimone

Exploring Mechanotransduction In Cerebral Cavernous Malformation

10:40 - 10:50

sciforum-070029: Hasan Safwan-Zaiter

The senescence marker p16Ink4a a player of liver endothelial cells physiology

10:50 - 10:55 Q&A
Break Time 10:55 - 11:10
Session 7. Cell Motility and Adhesion

Session Chair: Prof. Dr. Francisco Rivero
11:10 - 11:35

Invited Speaker Prof. Dr. Alexander Dityatev

Regulation of extrasynaptic glutamatergic signaling by polysialylated NCAM in health and disease

11:35 - 11:40 Q&A
11:40 - 11:50

sciforum-064990: Chaiyaboot Ariyachet

MicroRNA-223 Suppresses Human Hepatic Stellate Cell Activation Partly via Regulating the Actin Cytoskeleton and Alleviates Fibrosis in Organoid Models of Liver Injury

11:50 - 12:00

sciforum-068775: Ayechew Adera Getu

MST4: A Potential Oncogene and Therapeutic Target in Breast Cancer

12:00 - 12:10

sciforum-068816: Chiara Mazziotta

Hsa-microRNA-1249-3p modulates human epithelial cell clonogenicity via Homeobox A13 gene regulation

12:10 - 12:20

sciforum-070413: Marianne Best

Exploring the effect of PAK inhibition in a 3D Pancreatic Cancer invasion model

12:20 - 12:35 Q&A
Break Time 12:35 - 12:50
12:50 - 13:15

Invited Speaker Dr. Patrick Caswell

The Rab11 family controls signalling to the cytoskeleton for cell migration and invasion

13:15 - 13:20 Q&A
Lunch break 13:20 - 14:30
14:30 - 14:35 Awards ceremony
End of day 3 - closing

Instructions for Authors

Instructions

The conference "Cells 2023 - Cells, Cells and Nothing but Cells: Discoveries, Challenges and Directions" will accept abstracts only.

Please note that abstract submission and conference registration are two separate processes.

To register for the conference, please follow this link.

To present your research at the event

  • Create an account on Sciforum if you do not have one, then click on ‘New Submission’ on the upper-right corner of the window, or by clicking on ‘Submit Abstract’ at the top of this webpage.
  • Indicate what thematic area is best suited for your research.
  • Submit an abstract in English - the word limits are minimum 150 words and maximum 300 words.
  • Accepted abstracts will be published as a Book of Abstracts in MDPI Journal Biology and Life Sciences Forum. When uploading your abstract, please make sure to upload this template as PDF file.
  • The deadline to submit your abstract is 16 December 2022. The Conference Committee will notify the acceptance of your poster presentation by 20 January 2022.
  • Upon submission, you can select if you wish to also be considered for oral presentation. Following assessment by the Session Chairs, you will be notified by 20 January 2022 in a separate email whether your contribution has been accepted for oral presentation.
  • Please note that, in order to finalize the scientific program in due time, at least one registration by any of the authors, denoted as Covering Author, is required to cover the presentation and publication of any accepted abstract. Covering Author registration deadline is 6 February 2023. Your abstract will be withdrawn if your registration is not complete by this date.

Oral Presentations

Short talks will be 10 min long and will be followed by a Questions and Answers time at the end.

All presentations must be sent to the conference secretariat in advance so that, in case you are encountering technical difficulties, we could share your slides to the audience.

Poster Information

General information on the posters can be found by clicking here.

Potential Conflicts of Interest

It is the authors' responsibility to identify and declare any personal circumstances or interests that may be perceived as inappropriately influencing the representation or interpretation of clinical research. If there is no conflict, please state here "The authors declare no conflict of interest." This should be conveyed in a separate "Conflict of Interest" statement preceding the "Acknowledgments" and "References" sections at the end of the manuscript. Financial support for the study must be fully disclosed under the "Acknowledgments" section.

List of accepted submissions (49)

Id Title Authors
sciforum-064284 Molecular genetics for probiotic engineering: How fermentatable sugars affect aggregation, adhesion and agression in Lactobacillaceae

, , ,

Submitted: 26 Jul 2022

Abstract: Show Abstract
, , , Show Abstract
sciforum-064438 Characterization of glial response during retinal degeneration / regeneration in experimental laser models

, , , ,

Submitted: 19 Oct 2022

Abstract: Show Abstract
, , , , Show Abstract
sciforum-064990 MicroRNA-223 Suppresses Human Hepatic Stellate Cell Activation Partly via Regulating the Actin Cytoskeleton and Alleviates Fibrosis in Organoid Models of Liver Injury



Submitted: 26 Aug 2022

Abstract: Show Abstract
Show Abstract
sciforum-065301 New approaches targeting the invasive phenotype of prostate cancer-associated fibroblasts , , , Show Abstract
sciforum-067012 Identification of an Inherent Bioenergetic and Metabolic Phenotype in Late-Onset Alzheimer Disease

, , , ,

Submitted: 07 Oct 2022

Abstract: Show Abstract
, , , , Show Abstract

Event Awards

To acknowledge the support of the conference esteemed authors, and to recognize their outstanding scientific accomplishments, we are pleased to announce that the Cells journal is offering two awards: Best Oral Presentation and Best Poster.

The Awards
Best Oral Presentation Award

Number of Awards Available: 1

CHF 500.-
Best Poster Award

Number of Awards Available: 1

CHF 500.-

Sponsors and Partners

We are happy to share with you our Sponsorship Agenda, and invite you and your company to participate in and sponsor our Cells2023 conference!

Information on sponsorship levels and the benefits can be found directly in the Agenda itself. If you have any questions or wish to discuss options further, please do not hesitate to contact the Conference Secretariat. We thank you for your consideration!

Organizers


Media Partners

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